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Latent class analysis was applied to identify different patterns of chronic conditions. Logistic regression was implemented to examine relationships between multimorbidity patterns and risk of SCD-related functional difficulties.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Five multimorbidity patterns were identified: severely impaired (14.6%), respiratory\/depression (18.2%), obesity\/diabetes (18.6%), age-associated (22.3%), and minimal chronic conditions group (26.3%). Compared with minimal chronic conditions group, severely impaired group was most likely to report SCD-related functional difficulties, followed by respiratory\/depression and obesity\/diabetes group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussions<\/jats:title>\n                    <jats:p>Individuals in the three multimorbidity groups had elevated risk of SCD-related functional difficulties compared with minimal chronic conditions group. Characteristics of the high-risk groups identified in this study may help in development and implementation of interventions to prevent serious consequences of having multiple chronic conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08982643221080287","type":"journal-article","created":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T23:11:54Z","timestamp":1648163514000},"page":"929-938","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Multimorbidity Patterns in US Adults with Subjective Cognitive Decline and Their Relationship with Functional Difficulties"],"prefix":"10.1177","volume":"34","author":[{"given":"Yixiu","family":"Liu","sequence":"first","affiliation":[{"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Depeng","family":"Jiang","sequence":"additional","affiliation":[{"name":"University of Manitoba"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,3,24]]},"reference":[{"key":"e_1_3_5_2_1","unstructured":"Alzheimer\u2019s Association International Conference (2019). 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