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This study investigated the association between polypharmacy and somnolence symptoms (excessive sleepiness or long sleep duration).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from the National Social Life, Health, and Aging Project (NSHAP) 2010\u20132011 was used to examine the concurrent use of medications with potential somnolence as an adverse effect and the prevalence of somnolence symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 2638 older adults (mean, 71\u00a0years), 49.0% used medications with potential somnolence adverse effects. The adjusted prevalence of somnolence symptoms was significantly higher among those using three or more medications (58%) than those not using such medications (31.2%) (difference, 20.4%; 95% CI 12.5, 28.4).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>In this cross-sectional study, medications with somnolence as a potential adverse effect were commonly used, and the findings suggest a link between polypharmacy and the increased risk of somnolence symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/08982643241298734","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:52:23Z","timestamp":1732668743000},"page":"721-732","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Use of Medications With Somnolence Adverse Effects and Somnolence Symptoms Among Older Adults in the U.S."],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7804-0780","authenticated-orcid":false,"given":"Jocelyn","family":"Wilder","sequence":"first","affiliation":[{"name":"NORC at the University of Chicago"},{"name":"University of Illinois at Chicago"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Lauderdale","sequence":"additional","affiliation":[{"name":"University of Chicago"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dima M.","family":"Qato","sequence":"additional","affiliation":[{"name":"University of Southern California Alfred E. 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