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This study presents a case series wherein periodontal tissue regeneration therapy using a mixture of autogenous bone and platelet-rich plasma (PRP) was performed in 4 dogs with periodontitis. The advantage of both autogenous bone and PRP in periodontal tissue regeneration therapy has been reported previously. In addition, there are no limitations in accessing either of these materials, as they are obtained from the animal that is being treated. Periodontal tissue regeneration was achieved with attachment gain in 3 of 4 cases that was equivalent to that of trafermin, which was used as a positive control (autogenous bone and PRP: 3.5\u2009\u00b1\u20090.50 mm, trafermin: 4.2\u2009\u00b1\u20091.09 mm). Similar results were observed in root bifurcation lesions. The study concluded that mixtures of autogenous bone and PRP are a viable choice for periodontal tissue regeneration therapy in dogs, especially when there are limitations in the availability of periodontal regeneration materials.<\/jats:p>","DOI":"10.1177\/08987564251331112","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T03:11:06Z","timestamp":1745809866000},"page":"160-169","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Infrabony Periodontal Pocket Therapy With Autogenous Bone and Platelet-Rich Plasma in Dogs: A Case Series"],"prefix":"10.1177","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3336-990X","authenticated-orcid":false,"given":"Kazuya","family":"Tamura","sequence":"first","affiliation":[{"name":"Tamura Animal Clinic, Okayama City, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,4,28]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1999.214.09.1336"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.1"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/med.20144"},{"issue":"8","key":"e_1_3_3_5_2","first-page":"491","article-title":"Periodontal tissue regeneration using trafermin in periodontitis of dogs","volume":"72","author":"Tamura K","year":"2019","unstructured":"Tamura K, Nagahara Y. 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