{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T11:08:36Z","timestamp":1779361716250,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T00:00:00Z","timestamp":1763856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Sponsor: Peoples\u2019 Friendship University of Russia named after Patrice Lumumba.","award":["project No 0321040000"],"award-info":[{"award-number":["project No 0321040000"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Risk &amp; Safety in Medicine"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>COVID-19-associated thrombotic complications became a major problem of pandemic. Clinical practice guidelines are meant to present approaches to preventing and managing them. In our previous studies, we found that direct oral anticoagulants (DOACs) consumption and expenditure in Russia through COVID-19 pandemic was extensive, exceeding CPGs\u2019 recommendations in 2020 and 2021, particularly in outpatient settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze Russian clinical practice guidelines on the use of DOACs for COVID-19.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted thematic content analysis of Russian guidelines using qualitative research methods. Purposive sampling allowed including all existing guidelines on the use of DOACs in COVID-19 pandemic. The sample size was limited to the results of our previous searches of the Russian guideline and bibliographic databases. We focused on indications, contraindications, dosing regimens, monitoring, and drug interactions and compared with international recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Only one guideline advised against outpatient DOAC use for COVID-19, aligning with international standards. The guidelines lacked clarity on indications, dosing, and treatment duration. Only two of six guidelines included safety monitoring recommendations, while four provided precautions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We conclude that the found textual problems could potentially cause the established excessive consumption of direct oral anticoagulants in outpatients with COVID-19 on the rise the pandemic.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09246479251401348","type":"journal-article","created":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T16:00:04Z","timestamp":1763913604000},"page":"249-256","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Why national consumption of direct oral anticoagulants over the rise of COVID-19 pandemic exceeded all potential recommendations: A qualitative analysis of textual details of Russian clinical practice guidelines"],"prefix":"10.1177","volume":"37","author":[{"given":"Elena A.","family":"Baybulatova","sequence":"first","affiliation":[{"name":"Peoples\u2019"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikhail S.","family":"Chenkurov","sequence":"additional","affiliation":[{"name":"Peoples\u2019"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey K.","family":"Zyryanov","sequence":"additional","affiliation":[{"name":"Peoples\u2019"},{"name":"State Budgetary Institution of Healthcare of the City of Moscow \u201cCity Clinical Hospital No. 24 of the Moscow City Health Department\u201d"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliya E.","family":"Ziganshina","sequence":"additional","affiliation":[{"name":"Peoples\u2019"},{"name":"Cochrane Russia at the Russian Medical Academy for Continuous Professional Education of the Ministry of Health of the Russian Federation"},{"name":"Kazan State Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,11,23]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/HS9.0000000000000526"},{"issue":"3","key":"e_1_3_3_3_2","first-page":"CD013739","article-title":"Anticoagulants for people hospitalised with COVID-19","volume":"3","author":"Flumignan RL","year":"2022","unstructured":"Flumignan RL, Civile VT, Tin\u00f4co JDS, et al. Anticoagulants for people hospitalised with COVID-19. Cochrane Database Syst Rev 2022; 3(3): CD013739.","journal-title":"Cochrane Database Syst Rev"},{"issue":"8","key":"e_1_3_3_4_2","first-page":"CD015102","article-title":"Prophylactic anticoagulants for non-hospitalised people with COVID-19","volume":"8","author":"Santos BC","year":"2023","unstructured":"Santos BC, Flumignan RL, Civile VT, et al. Prophylactic anticoagulants for non-hospitalised people with COVID-19. Cochrane Database Syst Rev 2023; 8(8): CD015102.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2023.06.023"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/pharma3010001"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.17816\/KMJ642398"},{"key":"e_1_3_3_8_2","volume-title":"Diagnostics and treatment of new coronavirus infections (COVID-19)","author":"Ministry of Health of the Russian Federation. Temporary Methodological Recommendations for Prevention","year":"2022","unstructured":"Ministry of Health of the Russian Federation. Temporary Methodological Recommendations for Prevention, Diagnostics and treatment of new coronavirus infections (COVID-19). Ministry of Health of the Russian Federation, 2022."},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.15829\/1728-8800-2021-3172"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.15829\/1728-8800-2021-2916"},{"issue":"1","key":"e_1_3_3_11_2","first-page":"8","article-title":"Guidelines for the diagnosis and treatment of circulatory diseases in the context of the COVID-19 pandemic","volume":"1","author":"Shlyakho EV","year":"2020","unstructured":"Shlyakho EV, Konradi AO, Arutyunov GP, et al. Guidelines for the diagnosis and treatment of circulatory diseases in the context of the COVID-19 pandemic. Russ J Cardiol 2020; 1(1): 8\u201327.","journal-title":"Russ J Cardiol"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.21320\/1818-474X-2020-S1-9-120"},{"key":"e_1_3_3_13_2","first-page":"3","volume-title":"Problems of Standardization in Healthcare","author":"Vorobyev PA","year":"2021","unstructured":"Vorobyev PA (ed). Recommendations for the outpatient management of COVID-19 patients with the acute infection POST-COVID syndrome (issued by the Moscow city scientific society of physicians). In: Problems of Standardization in Healthcare. MGNOT, 2021, vol 7\u20138, pp. 3\u201396."},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/jth.15808"}],"container-title":["International Journal of Risk &amp; Safety in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09246479251401348","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09246479251401348","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09246479251401348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T10:58:58Z","timestamp":1779361138000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09246479251401348"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,23]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1177\/09246479251401348"],"URL":"https:\/\/doi.org\/10.1177\/09246479251401348","relation":{"has-review":[{"id-type":"doi","id":"10.1177\/09246479251401348\/v1\/decision1","asserted-by":"object"}]},"ISSN":["0924-6479","1878-6847"],"issn-type":[{"value":"0924-6479","type":"print"},{"value":"1878-6847","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,23]]}}}