{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:25:51Z","timestamp":1793787951376,"version":"4.6.1"},"reference-count":41,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Risk &amp; Safety in Medicine"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acute Inflammatory Demyelinating Polyradiculoneuropathy (AIDP), the most common form of Guillain-Barr\u00e9 Syndrome (GBS), may rarely be complicated by myocarditis, which results from an inflammatory or autoimmune response. Conversely, acute kidney injury (AKI), caused by osmotic nephrosis, is an uncommon adverse effect associated with maltose-based intravenous immunoglobulin (IVIG) therapy, a common treatment for GBS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 41-year-old diabetic male diagnosed with AIDP received maltose-based IVIG. After 75\u00a0g administration, he developed flu-like symptoms and AKI, followed by signs of myocarditis, including elevated troponin, reduced ejection fraction, and ECG changes. IVIG was discontinued early due to these adverse effects. The patient required ICU care and hemofiltration but recovered with supportive treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case highlights myocarditis as a rare complication of GBS and demonstrates that IVIG, while essential in treatment, even though maltose based, can lead to serious adverse effects including AKI, particularly in high-risk patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09246479261476841","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T07:25:56Z","timestamp":1786519556000},"page":"567-572","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Guillain-Barr\u00e9 syndrome complicated by myocarditis and acute kidney injury after maltose-based IVIG treatment: A case report"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5558-4305","authenticated-orcid":false,"given":"Anjusha K.","family":"Johnson","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy, Karpagam Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joby Thomas","family":"Mammen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Karpagam Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Priya","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice, Karpagam College of Pharmacy, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dharini","family":"Bhoopathi","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Karpagam Faculty of Medical Sciences and Research"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/20503121241239538"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.06.069"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2013.01.005"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/ene.16365"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000529110"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.4103\/2249-4863.130335"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-019-0250-9"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-022-02676-4"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00339-1"},{"issue":"3","key":"e_1_3_6_11_2","first-page":"e57066","article-title":"Treatment efficacy of plasmapheresis versus intravenous immunoglobulin in Guillain-Barr\u00e9 syndrome management: a systematic review","volume":"16","author":"Savithri NS","year":"2024","unstructured":"Savithri NS, Kasagga A, Hawrami C, et al. 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