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Explainable Artificial Intelligence (XAI), nano-enabled biosensors, digital twins, and the Internet of Medical Things (IoMT) are examples of emerging technologies and ideas that are improving real-time, dependable, customized, and privacy-preserving diagnostic systems.\n                      \n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The change to proactive and predictive healthcare is being facilitated by AI-enhanced biosensing. It has a good chance in early diagnosis, better treatment planning as well as the decrease in healthcare expenses. Nevertheless, there are still challenges such as lack of data, generalization of models, regulatory authorization, and moral issues.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09287329261479178","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:46:48Z","timestamp":1790092008000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["AI-driven biosensing technology for early disease detection: A comprehensive review"],"prefix":"10.1177","author":[{"given":"Tanzeel Ur","family":"Rehman","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Education, Lahore, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khawaja Daim","family":"Asif Ansari","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Digital Technologies, University of East London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Zaeem","family":"Kahlid","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Department, University of Engineering and Technology Lahore (New Campus), Lahore, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jawwad","family":"Sami Ur Rahman","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Riphah International University, Islamabad, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Al-harbi","sequence":"additional","affiliation":[{"name":"Medical Imaging Department, King Abdullah bin Abdulaziz University Hospital, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lama","family":"Almudaimeegh","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amna","family":"Mohamed Ahmed","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuhal Y","family":"Hamd","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, College of Health and Rehabilitation Sciences, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babar","family":"Ali","sequence":"additional","affiliation":[{"name":"School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"key":"e_1_3_4_2_2","first-page":"1","article-title":"Global journal of medical and biomedical case reports smart biosensors: AI-driven analysis for personalized medicine and dentistry","volume":"1","author":"Falkner S.","year":"2025","unstructured":"Falkner S. 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