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The operating performance, tool durability and cutting damage to patients are influenced by the tool\u2019s sharpness, intensity and structure, whereas the cutting characteristics rely on interactions between the tool and the skull. In this study, an orthogonal cutting experiment during a craniotomy of fresh pig skulls was performed to investigate chip formation on the side cutting and face cutting of the skull using a high-speed camera. The cutting forces with different combinations of cutting parameters, such as the rake angle, clearance angle, depth of cut and cutting speed, were measured. The skull bone microstructure and cutting damage were observed by scanning electron microscope. Cutting models for different cutting approaches and various depths of cut were constructed and analyzed. The study demonstrated that the effects of shearing, tension and extrusion occur during chip formation. Various chip types, such as unit chips, splintering chips and continuous chips, were generated. Continuous pieces of chips, which are advisable for easy removal from the field of operation, were formed at greater depths of cut and tool rake angles greater than 10\u00b0. Cutting damage could be relieved with a faster recovery with clearance angles greater than 20\u00b0.<\/jats:p>","DOI":"10.1177\/0954411917727245","type":"journal-article","created":{"date-parts":[[2017,8,21]],"date-time":"2017-08-21T05:53:47Z","timestamp":1503294827000},"page":"959-974","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Investigating bone chip formation in craniotomy"],"prefix":"10.1177","volume":"231","author":[{"given":"He","family":"Huiyu","sequence":"first","affiliation":[{"name":"NERCHD, School of Electromechanical Engineering, Guangdong University of Technology, Guangzhou, China"},{"name":"Dongguan Technician College, Dongguan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wang","family":"Chengyong","sequence":"additional","affiliation":[{"name":"NERCHD, School of Electromechanical Engineering, Guangdong University of Technology, Guangzhou, 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