{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:32:55Z","timestamp":1787239975012,"version":"build-2736575974"},"reference-count":35,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T00:00:00Z","timestamp":1580860800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Proc Inst Mech Eng H"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:p>The extent to which load transfer in a diseased mandible with odontogenic tumour might influence the potential risk of pathological fracture has scarcely been investigated. The study sought to investigate the quantitative deviations in load transfer across healthy and cancer-affected (diseased) mandibles having odontogenic tumours. The effect of size of the tumours (small: 9\u2009mm diameter, large: 19\u2009mm diameter), and variation in bone mechanical (elastic) properties of the mandible on load transfer in cancer-affected mandibles during a mastication cycle have been investigated. Based on patient-specific computed tomography\u2013scan datasets, detailed three-dimensional finite element models of healthy and diseased mandibles were developed. High stresses of 25\u201330\u2009MPa and strains \u223c700\u2009\u00b5\u03b5 were observed in the healthy mandible during the right molar bite. However, marginal deviations were observed in principal stress distributions in the diseased mandibles with small- and large-sized tumours, as compared to the healthy mandible. Maximum principal strains of \u223c1474\u2009\u00b5\u03b5 were found in the body region adjacent to the symphysis region for small-sized tumour. Whereas for large-sized tumour, maximum strains of \u223c2700\u2009\u00b5\u03b5 were observed in the right buccal regions. Reduction in Young\u2019s modulus due to different stages of odontogenic tumours had a localised effect on the principal stress distributions, but triggered an abrupt increase in the principal tensile strains. It appears that there is a potential risk of pathological fracture for large-sized odontogenic tumour, owing to high tensile stresses and strains.<\/jats:p>","DOI":"10.1177\/0954411920904618","type":"journal-article","created":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T09:21:16Z","timestamp":1580894476000},"page":"486-495","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Load transfer across a mandible during a mastication cycle: The effects of odontogenic tumour"],"prefix":"10.1177","volume":"234","author":[{"given":"Abir","family":"Dutta","sequence":"first","affiliation":[{"name":"Advanced Technology Development Centre, Indian Institute of Technology Kharagpur, Kharagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaushik","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, Kharagpur, India"},{"name":"Department of Mechanical Engineering, Indian Institute of Technology Delhi, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkata Sundeep","family":"Seesala","sequence":"additional","affiliation":[{"name":"School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaushik","family":"Dutta","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Science and Research, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjan Rashmi","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Science and Research, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santanu","family":"Dhara","sequence":"additional","affiliation":[{"name":"School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0745-1448","authenticated-orcid":false,"given":"Sanjay","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, Kharagpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,2,5]]},"reference":[{"key":"bibr1-0954411920904618","unstructured":"Ferlay J, Soerjomataram I, Ervik M, et al. 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