{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T10:05:07Z","timestamp":1779617107759,"version":"3.53.1"},"reference-count":36,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Biomedical Special Project of the Major Science and Technology Special Program of Yunnan Province of China","award":["202502AA310034"],"award-info":[{"award-number":["202502AA310034"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82260297and12162016"],"award-info":[{"award-number":["82260297and12162016"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science and Technology Innovation Team for Research and Application of Female Pelvic Floor Dysfunctional Diseases in Yunnan Universities","award":["K1322142"],"award-info":[{"award-number":["K1322142"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Proc Inst Mech Eng H"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:p>\n                    The biomechanical mechanism between\n                    <jats:italic toggle=\"yes\">genital hiatus<\/jats:italic>\n                    (GH), intra-abdominal pressure (IAP) and pelvic organ prolapse (POP) is currently unclear. Therefore, two biomechanical models for comparative analysis are developed to discuss the biomechanical relations of IAP and GH with prolapse of\n                    <jats:italic toggle=\"yes\">anterior<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">posterior vaginal walls<\/jats:italic>\n                    (AVW and PVW) in the injured pelvic floor system. Based on the magnetic resonance imaging (MRI) of the pelvic floor of a healthy woman, we developed two 2D finite element models by using mechanical equivalence to represent the physiological and pathological states respectively. Both models contain hollow structure\n                    <jats:italic toggle=\"yes\">rectum<\/jats:italic>\n                    . We simulated biomechanical characteristics of POP progression under different IAP and GH values in the PVW injury. In the pathological state with an IAP of 83.9\u2009cmH\n                    <jats:sub>2<\/jats:sub>\n                    O, the descending displacement of the\n                    <jats:italic toggle=\"yes\">cervix<\/jats:italic>\n                    increased from 14.3 to 20.9\u2009mm when the GH increased from 10 to 40\u2009mm. The maximum stress of AVW and\n                    <jats:italic toggle=\"yes\">perineal body<\/jats:italic>\n                    (PB) rose from 0.343\u2009to\u20090.611\u2009MPa, from 0.190\u2009to\u20090.974\u2009MPa, respectively. Compared with the physiological state, the initial GH is a significant influence on POP progression. The increase of GH leads to a reduction or loss of biomechanical support for the\n                    <jats:italic toggle=\"yes\">bladder<\/jats:italic>\n                    . The influence of IAPs and GH interaction exacerbates the injury and mechanical imbalance in the pathological state, which triggers increased stress in the AVW and PB, the descending displacements of the cervix and PVM, and exacerbates POP progression.\n                  <\/jats:p>","DOI":"10.1177\/09544119261434622","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T03:42:41Z","timestamp":1778038961000},"page":"516-528","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Biomechanical effects of intra-abdominal pressure and genital hiatus on the pelvic floor in initial injury"],"prefix":"10.1177","volume":"240","author":[{"given":"Qiuyu","family":"Zheng","sequence":"first","affiliation":[{"name":"Faculty of Mechanical and Electrical Engineering, Kunming University of Science and Technology, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Li","sequence":"additional","affiliation":[{"name":"The First Department of Urology, The First Affiliated Hospital, Kunming Medical University, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenhua","family":"Gao","sequence":"additional","affiliation":[{"name":"The First Department of Urology, The First Affiliated Hospital, Kunming Medical University, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihong","family":"Shen","sequence":"additional","affiliation":[{"name":"The First Department of Urology, The First Affiliated Hospital, Kunming Medical University, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3727-7049","authenticated-orcid":false,"given":"Tingqiang","family":"Yao","sequence":"additional","affiliation":[{"name":"Faculty of Mechanical and Electrical Engineering, Kunming University of Science and Technology, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,5]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.10.040"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(92)91562-O"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-018-03859-9"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.174.3.1740657"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-015-1401-9"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.3659"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10237-023-01729-y"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2023.1292407"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2023.11.1247"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0b013e328357628b"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/09544119241237356"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.12.027"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000227786.69257.a8"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-1760-9"},{"key":"e_1_3_2_16_2","volume-title":"Biomechanical analyses of posterior vaginal prolapse: MR imaging and computer modeling studies","author":"Luo JJ","year":"2018","unstructured":"Luo JJ. Biomechanical analyses of posterior vaginal prolapse: MR imaging and computer modeling studies. 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