{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:36:22Z","timestamp":1777926982145,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:p>The aim of the work is to describe the occurrence of ocular complications and loss of vision due to herpes zoster ophthalmicus (HZO) in HIV-positive patients who received early antiviral therapy for HZO. This is a post hoc analysis of prospectively collected data. Twenty-four HIV-positive patients with HZO were included in this report; male to female ratio was 3.8:1; mean age was 33.5 (\u00b114.9) years. The visual outcome was good, with 14\/24 patients having 6\/6 vision; severe vision loss (\u22646\/60) occurred in only 2\/24. There was no statistical difference in the visual outcome between the HIV-positive and -negative patients ( P = 0.69), although severe vision loss was more likely in HIV-infected patients. The ocular complications of HZO in HIV-infected patients were: reduced corneal sensation (17\/24), corneal epithelial lesions (14\/24), uveitis (12\/24), elevated intraocular pressure (10\/24) and extra-ocular muscle palsy (3\/24). The severity of rash was similar in the two groups but multidermatomal rash occurred only in HIV-infected patients (4\/24). There was no difference in the occurrence of ocular complications of HZO between HIV-positive and HIV-negative patients. HZO associated ocular complications and visual loss is low in HIV-infected patients if treated with HZO antiviral therapy and was comparable with HIV-negative patients. Early institution of HZO antiviral therapy is recommended to reduce ocular complication and vision loss.<\/jats:p>","DOI":"10.1177\/0956462412472303","type":"journal-article","created":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T18:04:49Z","timestamp":1369937089000},"page":"106-109","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Ocular complications and loss of vision due to herpes zoster ophthalmicus in patients with HIV infection and a comparison with HIV-negative patients"],"prefix":"10.1177","volume":"24","author":[{"given":"S","family":"Nithyanandam","sequence":"first","affiliation":[{"name":"Department of Ophthalmology St John's Medical College, Bangalore 560034, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Joseph","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology St John's Medical College, Bangalore 560034, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Stephen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, St John's Medical College, Bangalore 560034, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,5,6]]},"reference":[{"key":"bibr1-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199909000-00002"},{"key":"bibr2-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(05)80021-9"},{"key":"bibr3-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/157.2.314"},{"key":"bibr4-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.1992.tb01622.x"},{"key":"bibr5-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2003.00057.x"},{"key":"bibr6-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1983.01040010044004"},{"key":"bibr7-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(99)80133-0"},{"key":"bibr8-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(86)90585-4"},{"key":"bibr9-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(86)33678-9"},{"key":"bibr10-0956462412472303","first-page":"70","volume":"8","author":"Aylward GW","year":"1994","journal-title":"Influence of oral acyclovir on ocular complications of herpes zoster ophthalmicus eye"},{"key":"bibr11-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1086\/513626"},{"key":"bibr12-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(94)31099-2"},{"key":"bibr13-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1258\/0956462981922656"},{"key":"bibr14-0956462412472303","doi-asserted-by":"publisher","DOI":"10.4314\/njm.v19i2.56508"},{"key":"bibr15-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000178408.62675.b0"},{"key":"bibr16-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.71.11.806"},{"key":"bibr17-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2010.02352.x"},{"key":"bibr18-0956462412472303","unstructured":"Colenbrander A, for The International Council of Ophthalmology, 29th International Congress of Ophthalmology, Sydney, Australia, April 2002"},{"key":"bibr19-0956462412472303","doi-asserted-by":"publisher","DOI":"10.7196\/SAMJ.3191"},{"key":"bibr20-0956462412472303","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(01)00703-3"},{"key":"bibr21-0956462412472303","first-page":"467","volume":"73","author":"McNulty A","year":"1997","journal-title":"Genitourin Med"},{"key":"bibr22-0956462412472303","doi-asserted-by":"publisher","DOI":"10.3109\/02713689109020376"}],"container-title":["International Journal of STD &amp; 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