{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:36:29Z","timestamp":1777926989440,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>We estimated the burden of HIV-associated neurocognitive disorders (HAND) in a UK clinic. From a random sample, and referrals to specialist services over one year (neurology, clinical psychology, hospital admissions), we determined whether patients were diagnosed with HIV-associated dementia (HAD) and whether they reported symptoms suggesting neurocognitive impairment (NCI). In the first sample, 2\/150 (prevalence 1.3%; 95% confidence interval [CI] 0.2\u20134.7%) had documented HAD. Eleven patients (7.3%; CI 3.7\u201312.7%) reported recent symptoms suggesting NCI; most of these individuals were diagnosed with a psychiatric or substance-use disorder. Among specialist referrals with symptoms suggesting NCI, 11 were diagnosed with HAD from a clinic population of 3129 individuals (annual incidence 0.4%; CI 0.2\u20130.6%). No patients with mildly symptomatic or asymptomatic HAND were identified in either sample, suggesting that such patients remain undetected in current clinical practice. Evidence-based screening for HAND in HIV clinics may be needed.<\/jats:p>","DOI":"10.1177\/0956462412472452","type":"journal-article","created":{"date-parts":[[2013,6,24]],"date-time":"2013-06-24T18:45:53Z","timestamp":1372099553000},"page":"217-219","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Routine detection and management of neurocognitive impairment in HIV-positive patients in a UK centre"],"prefix":"10.1177","volume":"24","author":[{"given":"L J","family":"Haddow","sequence":"first","affiliation":[{"name":"Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, University College London"},{"name":"Camden Provider Services, Central and North West London NHS Foundation Trust"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A Accoroni","family":"Cpsychoil","sequence":"additional","affiliation":[{"name":"Camden Provider Services, Central and North West London NHS Foundation Trust"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J D","family":"Cartledge","sequence":"additional","affiliation":[{"name":"Camden Provider Services, Central and North West London NHS Foundation Trust"},{"name":"University College London Hospitals NHS Foundation Trust. London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Manji","sequence":"additional","affiliation":[{"name":"Camden Provider Services, Central and North West London NHS Foundation Trust"},{"name":"University College London Hospitals NHS Foundation Trust. London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Benn","sequence":"additional","affiliation":[{"name":"Camden Provider Services, Central and North West London NHS Foundation Trust"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R J C","family":"Gilson","sequence":"additional","affiliation":[{"name":"Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, University College London"},{"name":"Camden Provider Services, Central and North West London NHS Foundation Trust"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,5,6]]},"reference":[{"key":"bibr1-0956462412472452","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283354a7b"},{"key":"bibr2-0956462412472452","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000287431.88658.8b"},{"key":"bibr3-0956462412472452","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1212\/WNL.41.6.778","volume":"41","author":"Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus-type 1 (HIV-1) infection.","year":"1991","journal-title":"Neurology"},{"key":"bibr4-0956462412472452","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/158.5.1079"},{"key":"bibr5-0956462412472452","doi-asserted-by":"publisher","DOI":"10.2217\/hiv.10.23"},{"key":"bibr6-0956462412472452","unstructured":"Winston A, Arenas-Pinto A, Stoehr W, Factors Influencing Neurocognitive Function in a Large Cohort of HIV infected Patients on Effective Antiretroviral Therapy. 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