{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:36:53Z","timestamp":1777927013377,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2013,7,15]],"date-time":"2013-07-15T00:00:00Z","timestamp":1373846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:p>Anal squamous cell carcinoma is more common in HIV-positive homosexual men than in the general population and prognosis worsens with increasing tumour size. To identify opportunities for earlier diagnosis, we aimed to determine size and visibility of anal squamous cell carcinoma at diagnosis. We conducted a retrospective review of medical records between 1992 and 2010 from one hospital radiotherapy centre, a major centre for HIV care, in Melbourne, Australia. Of 128 cases of anal squamous cell carcinoma, 24 (19%) were in HIV-positive men. At diagnosis, half (52%) of the tumours were externally visible and mean estimated tumour size was 36\u2009mm (29\u2009mm in HIV-positive and 38\u2009mm in HIV-negative patients; p\u2009=\u20090.04) and 114\/121 (94%) tumours were 1\u2009cm or larger. The most frequent symptoms were bleeding (43%) and pain (36%) and mean duration of symptoms was 22 weeks. This suggests most anal squamous cell carcinoma were visible or palpable for some time before diagnosis, meaning that screening high-risk groups by anal inspection and palpation is plausible.<\/jats:p>","DOI":"10.1177\/0956462413486776","type":"journal-article","created":{"date-parts":[[2013,7,15]],"date-time":"2013-07-15T21:45:00Z","timestamp":1373924700000},"page":"879-882","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Size of anal squamous cell carcinomas at diagnosis: a retrospective case series"],"prefix":"10.1177","volume":"24","author":[{"given":"TRH","family":"Read","sequence":"first","affiliation":[{"name":"Melbourne Sexual Health Centre, Alfred Health, Melbourne, Australia"},{"name":"Melbourne School of Population Health and Global Health, University of Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KL","family":"Huson","sequence":"additional","affiliation":[{"name":"The Alfred Hospital, Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JL","family":"Millar","sequence":"additional","affiliation":[{"name":"William Buckland Radiotherapy Centre, Alfred Health, Melbourne, Australia"},{"name":"Dept of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Haydon","sequence":"additional","affiliation":[{"name":"The Alfred Hospital, Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"IWT","family":"Porter","sequence":"additional","affiliation":[{"name":"William Buckland Radiotherapy Centre, Alfred Health, Melbourne, Australia"},{"name":"Department of Surgery, Monash University, Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AE","family":"Grulich","sequence":"additional","affiliation":[{"name":"Kirby Institute, University of New South Wales, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JS","family":"Hocking","sequence":"additional","affiliation":[{"name":"Centre for Women\u2019s Health, Gender and Society, University of Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MY","family":"Chen","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre, Alfred Health, Melbourne, Australia"},{"name":"Melbourne School of Population Health and Global Health, University of Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CS","family":"Bradshaw","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre, Alfred Health, Melbourne, Australia"},{"name":"Dept of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CK","family":"Fairley","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre, Alfred Health, Melbourne, Australia"},{"name":"Melbourne School of Population Health and Global Health, University of Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,7,15]]},"reference":[{"key":"bibr1-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.01.015"},{"key":"bibr2-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70080-3"},{"key":"bibr3-0956462413486776","volume-title":"SEER survival monograph: cancer survival among adults: US SEER Program, 1988-2001, Patient and Tumor Characteristics","author":"Madeleine MM","year":"2007"},{"key":"bibr4-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.09.060"},{"key":"bibr5-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-007-9154-7"},{"key":"bibr6-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1007\/DCR.0b013e3181a65f5f"},{"key":"bibr7-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3281c61201"},{"key":"bibr8-0956462413486776","unstructured":"Guideline: Neoplastic complications of HIV infection. New York State Department of Health 2007."},{"key":"bibr9-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1016\/j.jana.2011.08.006"},{"key":"bibr10-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e32831a6fe0"},{"key":"bibr11-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1071\/SH10152"},{"key":"bibr12-0956462413486776","first-page":"1","volume":"58","author":"Mofenson LM","year":"2009","journal-title":"MMWR Recomm Rep"},{"key":"bibr13-0956462413486776","unstructured":"Wilson JWG and Jungner G.\n                      Principles and practice of screening for disease\n                      . In:\n                      Public Health Papers.\n                      Geneva: World Health Organisation, 1968."},{"key":"bibr14-0956462413486776","unstructured":"Edge SBB, Byrd DR, Compton CC, et\u00a0al. (eds)\n                      American Joint Committee on Cancer Staging Manual\n                      . 7th ed. Berlin, Germany: Springer, 2010, pp. 167\u2013169."},{"key":"bibr15-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19840701)54:1<114::AID-CNCR2820540124>3.0.CO;2-P"},{"key":"bibr16-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d6818"},{"key":"bibr17-0956462413486776","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr050"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462413486776","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462413486776","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462413486776","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:32:30Z","timestamp":1777674750000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462413486776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,15]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1177\/0956462413486776"],"URL":"https:\/\/doi.org\/10.1177\/0956462413486776","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,15]]}}}