{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:37:13Z","timestamp":1777927033152,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2013,11,27]],"date-time":"2013-11-27T00:00:00Z","timestamp":1385510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:p>Summary<\/jats:p>\n                  <jats:p>Although antiretroviral therapy has revolutionized the care of HIV-infected patients, it has been associated with metabolic abnormalities. Hence, this study was planned to investigate the effects of fish oil on lipid profile, insulin resistance, and body fat distribution in HIV-infected Brazilian patients on antiretroviral therapy, considering that marine omega-3 fatty acids seem to improve features of the metabolic syndrome. We conducted a randomized, parallel, placebo-controlled trial that assessed the effects of 3\u2009g fish oil\/day (540\u2009mg of eicosapentaenoic acid plus 360\u2009mg of docosahexaenoic acid) or 3\u2009g soy oil\/day (placebo) on 83 HIV-infected Brazilian men and non-pregnant women on antiretroviral therapy.<\/jats:p>\n                  <jats:p>No statistically significant relationships between fish oil supplementation and longitudinal changes in triglyceride ( p\u2009=\u20090.335), low-density lipoprotein cholesterol ( p\u2009=\u20090.078), high-density lipoprotein cholesterol ( p\u2009=\u20090.383), total cholesterol ( p\u2009=\u20090.072), apolipoprotein B ( p\u2009=\u20090.522), apolipoprotein A1 ( p\u2009=\u20090.420), low-density lipoprotein cholesterol\/apolipoprotein B ratio ( p\u2009=\u20090.107), homeostasis model assessment for insulin resistance index ( p\u2009=\u20090.387), body mass index ( p\u2009=\u20090.068), waist circumference ( p\u2009=\u20090.128), and waist\/hip ratio ( p\u2009=\u20090.359) were observed. A low dose of fish oil did not alter lipid profile, insulin resistance, and body fat distribution in HIV-infected patients on antiretroviral therapy.<\/jats:p>","DOI":"10.1177\/0956462413513748","type":"journal-article","created":{"date-parts":[[2013,11,27]],"date-time":"2013-11-27T22:31:50Z","timestamp":1385591510000},"page":"96-104","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Effects of fish oil on lipid profile and other metabolic outcomes in HIV-infected patients on antiretroviral therapy: a randomized placebo-controlled trial"],"prefix":"10.1177","volume":"25","author":[{"given":"Julicristie M","family":"Oliveira","sequence":"first","affiliation":[{"name":"School of Applied Sciences, University of Campinas, Limeira, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia HC","family":"Rond\u00f3","sequence":"additional","affiliation":[{"name":"Department of Nutrition, School of Public Health, University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John S","family":"Yudkin","sequence":"additional","affiliation":[{"name":"University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 MP","family":"Souza","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Public Health, University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiane N","family":"Pereira","sequence":"additional","affiliation":[{"name":"Department of Nutrition, School of Public Health, University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea W","family":"Catalani","sequence":"additional","affiliation":[{"name":"Department of Nutrition, School of Public Health, University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila M","family":"Picone","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Medical School, University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aluisio AC","family":"Segurado","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Medical School, University of Sao Paulo, Sao Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,11,27]]},"reference":[{"key":"bibr1-0956462413513748","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200305230-00010"},{"key":"bibr2-0956462413513748","first-page":"112","volume":"18","author":"Grunfeld C","year":"2010","journal-title":"Top HIV Med"},{"key":"bibr3-0956462413513748","doi-asserted-by":"publisher","DOI":"10.1310\/hct1205-268"},{"key":"bibr4-0956462413513748","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/87.6.1981S"},{"key":"bibr5-0956462413513748","doi-asserted-by":"publisher","DOI":"10.1310\/hct0806-400"},{"key":"bibr6-0956462413513748","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2010.04.012"},{"key":"bibr7-0956462413513748","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2006000300008"},{"key":"bibr8-0956462413513748","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/36.5.936"},{"key":"bibr9-0956462413513748","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/77.5.1171"},{"key":"bibr10-0956462413513748","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2004.01.007"},{"key":"bibr11-0956462413513748","unstructured":"Programa de Apoio a Nutri\u00e7\u00e3o \u2013 NutWin [software].Departamento de Inform\u00e1tica em Sa\u00fade. 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