{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T22:59:57Z","timestamp":1781218797838,"version":"3.54.1"},"reference-count":18,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2014,2,3]],"date-time":"2014-02-03T00:00:00Z","timestamp":1391385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>\n                    Kaposi\u2019s sarcoma (KS) is an AIDS-defining condition. Typically, KS affects the skin with or without visceral involvement. The extensive use of antiretroviral therapy (ART) has decreased the incidence of KS amongst the HIV-positive population. We report a case of a 40-year-old man with HIV-1 infection with CD4 count of 551 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    and an undetectable viral load who presented with two skin-coloured KS lesions on the prepuce of the penis. Diagnosis was confirmed by histopathology. He had been commenced on ART three years earlier with a nadir CD4 count of 255 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    . He had achieved and maintained viral suppression since commencing ART. The patient was initially treated with cryotherapy and 5% imiquimod as the lesions were presumed to be warts. The lack of response to treatment prompted further investigation. We carried out a literature search of published cases of penile KS over the past 10 years. The majority of articles regarding penile KS were published in the pre-ART era and involved patients with AIDS. Over the past 10 years, published cases of penile KS have almost exclusively been in HIV-negative men. We found 10 published cases of penile KS in HIV-negative men and only one other published case of penile KS in a HIV-positive man, who had severe immune suppression with CD4 count below 200 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    . This is the first case report to describe a HIV-positive patient stable on ART with a CD4 count above 200 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    and suppressed HIV-1 viral load, to develop two KS lesions on the penis. Clinicians have to remain suspicious of penile lesions and appreciate the crucial role a biopsy with histopathological analysis plays in confirming a diagnosis. In addition, this case illustrates that unusual presentations of KS can still occur in treated HIV-positive patients with sustained immune recovery.\n                  <\/jats:p>","DOI":"10.1177\/0956462413517494","type":"journal-article","created":{"date-parts":[[2014,2,3]],"date-time":"2014-02-03T23:48:14Z","timestamp":1391471294000},"page":"607-610","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Isolated penile Kaposi\u2019s sarcoma in a HIV-positive patient stable on treatment for three years"],"prefix":"10.1177","volume":"25","author":[{"given":"Dornubari","family":"Lebari","sequence":"first","affiliation":[{"name":"Blackpool Sexual Health Services, Whitegate Health Centre, Blackpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesal","family":"Gohil","sequence":"additional","affiliation":[{"name":"University of Liverpool Medical School, Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lipsita","family":"Patnaik","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Blackpool Victoria Teaching Hospital, Blackpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wafaa","family":"Wasef","sequence":"additional","affiliation":[{"name":"Blackpool Sexual Health Services, Whitegate Health Centre, Blackpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,2,3]]},"reference":[{"key":"bibr1-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-3589(07)56016-3"},{"key":"bibr2-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(99)80236-2"},{"key":"bibr3-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)39129-2"},{"key":"bibr4-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(08)80739-6"},{"key":"bibr5-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)35435-6"},{"key":"bibr6-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc070508"},{"key":"bibr7-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.22.1823"},{"key":"bibr8-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01423.x"},{"key":"bibr9-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2003.00747.x"},{"key":"bibr10-0956462413517494","first-page":"12","volume":"17","author":"Pinto-Almeida T","year":"2011","journal-title":"Dermatol Online J"},{"key":"bibr11-0956462413517494","doi-asserted-by":"publisher","DOI":"10.3315\/jdcr.2011.1067"},{"key":"bibr12-0956462413517494","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2011.10039"},{"key":"bibr13-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962009000500013"},{"key":"bibr14-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-7310(08)74769-0"},{"key":"bibr15-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2006.01282.x"},{"key":"bibr16-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2005.01211.x"},{"key":"bibr17-0956462413517494","first-page":"582","volume":"13","author":"Pacifico A","year":"2003","journal-title":"Eur J Dermatol"},{"key":"bibr18-0956462413517494","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023239018160"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462413517494","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462413517494","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462413517494","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:33:15Z","timestamp":1777674795000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462413517494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,3]]},"references-count":18,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1177\/0956462413517494"],"URL":"https:\/\/doi.org\/10.1177\/0956462413517494","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,3]]}}}