{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T07:20:37Z","timestamp":1784704837945,"version":"3.55.0"},"reference-count":14,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T00:00:00Z","timestamp":1401840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>A retrospective case-notes review was undertaken of all women with lichen sclerosus seen during a 12-month period to review their characteristics and care. A total of 273 case-notes were reviewed. The mean age was 61 years (range, 14\u201394), and the mean duration of symptoms was 6.4 years (range, 1\u201350). The mean age at diagnosis was 55 years (range, 7\u201392). Sixty-two (23%) had at least one other autoimmune condition. Autoimmune conditions were seven times more frequent overall compared with United Kingdom prevalences. On-going symptoms were reported as none\/minimal in 196 (72%), moderate in 65 (24%) and severe in 12 (4%). A total of 233 women (85%) had on-going treatment with clobetasol propionate (Dermovate) ointment with a mode of eight applications per month (range, 0\u201330). Forty-three women (16%) reported sexual dysfunction and 13 (5%) had needed at least one surgical procedure to restore sexual function. Eighty-six (32%) had undergone at least one biopsy. Nine squamous cell cancers (3%) had been diagnosed in six women (2%). These patients were managed in line with all current guidance. It is surprising that there is still no evidence to direct long-term management.<\/jats:p>","DOI":"10.1177\/0956462414538419","type":"journal-article","created":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T22:13:16Z","timestamp":1402006396000},"page":"352-356","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["The management of lichen sclerosus in a genitourinary medicine setting: a 12-month retrospective case-notes review"],"prefix":"10.1177","volume":"26","author":[{"given":"Rachel","family":"Challenor","sequence":"first","affiliation":[{"name":"GUM Department, Derriford Hospital, Plymouth, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,6,4]]},"reference":[{"key":"bibr1-0956462414538419","unstructured":"http:\/\/www.bashh.org\/documents\/UK%20national%20guideline%20for%20the%20management%20of%20vulval%20conditions%202014.pdf (accessed 30 March 2014) 2014 UK National Guideline on the Management of Vulval Conditions (accessed 30 March 2014)."},{"key":"bibr2-0956462414538419","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09997.x"},{"key":"bibr3-0956462414538419","unstructured":"http:\/\/www.rcog.org.uk\/womens-health\/clinical-guidance\/management-vulval-skin-disorders-green-top-58 (accessed 30 March 2014) The Management of Vulval Skin Disorders Green-top Guideline 58."},{"key":"bibr4-0956462414538419","unstructured":"http:\/\/www.rightdiagnosis.com\/a\/ai\/stats-country.htm (accessed 30 March 2014) Statistics by country for autoimmune disease."},{"key":"bibr5-0956462414538419","unstructured":"http:\/\/www.british-thyroid-association.org\/info-for-patients\/ (accessed 30 March 2014)."},{"key":"bibr6-0956462414538419","unstructured":"http:\/\/www.patient.co.uk\/doctor\/Alopecia.htm (accessed 30 March 2014)."},{"key":"bibr7-0956462414538419","unstructured":"https:\/\/www.diabetes.org.uk\/Documents\/Reports\/Diabetes-in-the-UK-2012.pdf (accessed 30 March 2014) Diabetes in the UK 2012."},{"key":"bibr8-0956462414538419","unstructured":"http:\/\/cks.nice.org.uk\/vitiligo#!backgroundsub:1 (accessed 30 March 2014) Prevalence of Vitiligo."},{"key":"bibr9-0956462414538419","unstructured":"http:\/\/www.nhs.uk\/conditions\/anaemia-vitamin-b12-and-folate-deficiency\/Pages\/Introduction.aspx (accessed 30 March 2014) Anaemia, vitamin B12 or folate deficiency."},{"key":"bibr10-0956462414538419","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1988.tb01748.x"},{"key":"bibr11-0956462414538419","unstructured":"http:\/\/www.uptodate.com\/contents\/extragenital-lichen-sclerosus (accessed 25 April 2014)."},{"key":"bibr12-0956462414538419","unstructured":"http:\/\/dermnetnz.org\/immune\/lichen-sclerosus.html (accessed 25 April 2014)."},{"key":"bibr13-0956462414538419","unstructured":"http:\/\/www.bssvd.org\/images\/stories\/documents\/VULVAL%20LICHEN%20SCLEROSUS%20fu%20guidance%20for%20gps.pdf (accessed 3 April 2014)."},{"key":"bibr14-0956462414538419","unstructured":"http:\/\/www.patient.co.uk\/doctor\/vulval-cancer (accessed 30 March 2014)."}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462414538419","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462414538419","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462414538419","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:33:58Z","timestamp":1777674838000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462414538419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,4]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1177\/0956462414538419"],"URL":"https:\/\/doi.org\/10.1177\/0956462414538419","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,4]]}}}