{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:38:44Z","timestamp":1777927124574,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T00:00:00Z","timestamp":1468108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:p>There is a wide range of plasma cell abnormalities in people living with HIV (PLHIV). Extramedullary plasmacytomas are not common in HIV infection, unlike plasmablastic lymphomas. An HIV-positive 44-year-old man on antiretroviral therapy presented with a rapidly progressing swelling on the face. Imaging revealed underlying bone destruction. Histologically, there was a tumour composed of small to medium-sized plasmacytoid cells admixed with many mature plasma cells and plasmablasts. These were positive for CD138 and MUM 1. Extramedullary multiple myeloma was ruled out as CD56 and cyclin D-1 were negative. EBV was negative. As the tumour cells were mostly mature, plasmablastic lymphoma was also excluded. The presence of a monoclonal protein (1\u2009g%), IgG kappa type, was detected. Neoplasia of plasma cells acquires special clinical characteristics in PLHIV. These patients are younger, with a greater tendency to develop solitary extramedullary plasmacytomas with atypical clinical evolution and greater aggressiveness of the neoplastic process. All of these features, along with a high proliferation index (MIB1 60%) was found in our patient. We report this case for its rarity, histopathological dilemma and its atypical features in HIV infection.<\/jats:p>","DOI":"10.1177\/0956462415605244","type":"journal-article","created":{"date-parts":[[2015,9,23]],"date-time":"2015-09-23T20:07:58Z","timestamp":1443038878000},"page":"909-911","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Extramedullary plasmacytoma: an unusual neoplasm in a HIV-positive patient"],"prefix":"10.1177","volume":"27","author":[{"given":"Anjana A","family":"Joseph","sequence":"first","affiliation":[{"name":"Department of Dermatology, Christian Medical College Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Pulimood","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Christian Medical College Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie T","family":"Manipadam","sequence":"additional","affiliation":[{"name":"Department of Pathology, Christian Medical College Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Auro","family":"Viswabandya","sequence":"additional","affiliation":[{"name":"Department of Haematology, Christian Medical College Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elanthenral","family":"Sigamani","sequence":"additional","affiliation":[{"name":"Department of Pathology, Christian Medical College Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,10]]},"reference":[{"key":"bibr1-0956462415605244","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199803263381301"},{"key":"bibr2-0956462415605244","first-page":"47","volume":"85","author":"Galieni P","year":"2000","journal-title":"Haematologica"},{"key":"bibr3-0956462415605244","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(03)00092-9"},{"key":"bibr4-0956462415605244","doi-asserted-by":"publisher","DOI":"10.1186\/2050-7771-1-8"},{"key":"bibr5-0956462415605244","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.04834.x"},{"key":"bibr6-0956462415605244","doi-asserted-by":"publisher","DOI":"10.1002\/path.1680"},{"key":"bibr7-0956462415605244","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2000.078005601.x"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462415605244","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462415605244","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462415605244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:35:30Z","timestamp":1777674930000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462415605244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,10]]},"references-count":7,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1177\/0956462415605244"],"URL":"https:\/\/doi.org\/10.1177\/0956462415605244","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,10]]}}}