{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:39:07Z","timestamp":1777927147938,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T00:00:00Z","timestamp":1468108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2017,3]]},"abstract":"\n Trichomonas vaginalis (TV) rates in women are increasing and many are asymptomatic. Nucleic acid amplification tests (NAATs) are becoming the \u2018gold standard\u2019 for diagnosis. We aimed to establish our asymptomatic TV rates by testing all women attending Oxfordshire\u2019s Sexual Health service, regardless of symptoms, using the BD ProbeTec\u2122 TV Q\n x<\/jats:sup>\n NAATs (BDQ\n x<\/jats:sup>\n ). During BDQ\n x<\/jats:sup>\n \u2019s verification process, the sensitivity and specificity were calculated using results of 220 endocervical samples from symptomatic women, compared with culture. BDQ\n x<\/jats:sup>\n was subsequently implemented and prospectively evaluated over 6 months in female attendees. Wet mount microscopy was also performed in symptomatics. Demographic and clinical characteristics of those diagnosed were analysed. From 220 samples tested by BDQ\n x<\/jats:sup>\n and culture: 5 were positive on both and one solely using BDQ\n x<\/jats:sup>\n , giving a sensitivity and specificity of 100% and 99.53%, respectively. In the prospective cohort, of 5775 BDQ\n x<\/jats:sup>\n tests, 33 (0.57%) were positive. 11\/33 (33%) patients were asymptomatic. All patients diagnosed had risk factors: age >25 years (85%), residence in a deprived area (79%) and black ethnicity (21%). Despite BDQ\n x<\/jats:sup>\n being highly sensitive and specific, with our low TV prevalence universal screening may not be justified. Targeted screening using local demographic data merits further investigation.\n <\/jats:p>","DOI":"10.1177\/0956462416649888","type":"journal-article","created":{"date-parts":[[2016,5,6]],"date-time":"2016-05-06T00:18:33Z","timestamp":1462493913000},"page":"357-361","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Detecting asymptomatic\n Trichomonas vaginalis<\/i>\n in females using the BD ProbeTec\u2122\n Trichomonas vaginalis<\/i>\n Q\n x<\/sup>\n nucleic acid amplification test"],"prefix":"10.1177","volume":"28","author":[{"given":"Emily","family":"Lord","sequence":"first","affiliation":[{"name":"Department of Sexual Health, Oxford University Hospitals NHS Foundation Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tana","family":"Newnham","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oxford University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucy","family":"Dorrell","sequence":"additional","affiliation":[{"name":"Oxford NIHR Biomedical Research Centre, The University of Oxford, UK"},{"name":"Nuffield Department of Medicine, The University of Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Jesuthasan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oxford University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine","family":"Clarke","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oxford University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie","family":"Jeffery","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oxford University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jackie","family":"Sherrard","sequence":"additional","affiliation":[{"name":"Department of Sexual Health, Oxford University Hospitals NHS Foundation Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,10]]},"reference":[{"key":"bibr1-0956462416649888","unstructured":"Public Health England. All STI diagnoses and services by gender and sexual risk, 2010\u20132014, https:\/\/www.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/436729\/2014_Table_4_All_STI_diagnoses___services_by_gender___sexual_risk.pdf (accessed 20 August 2015)."},{"key":"bibr2-0956462416649888","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268813002902"},{"key":"bibr3-0956462416649888","doi-asserted-by":"publisher","DOI":"10.1258\/095646207781024892"},{"key":"bibr4-0956462416649888","doi-asserted-by":"publisher","DOI":"10.1177\/0956462414525947"},{"key":"bibr5-0956462416649888","doi-asserted-by":"publisher","DOI":"10.1086\/511278"},{"key":"bibr6-0956462416649888","unstructured":"British Association for Sexual Health and HIV Clinical Effectiveness Group. United Kingdom Guideline on the Management of\n Trichomonas vaginalis\n , http:\/\/www.bashh.org\/documents\/87\/87.pdf (2007, accessed 01 December 2015)."},{"key":"bibr7-0956462416649888","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02966-13"},{"key":"bibr8-0956462416649888","unstructured":"BD Molecular Diagnostics. ProbeTecTM\n Trichomonas vaginalis\n (TV) Qx Amplified DNA Assay, http:\/\/moleculardiagnostics.bd.com\/product\/viperxtr\/ (accessed 14 January 2016)."},{"key":"bibr9-0956462416649888","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2011.011102"},{"key":"bibr10-0956462416649888","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2014-051514"},{"key":"bibr11-0956462416649888","first-page":"A11","volume":"91","author":"Turner K","year":"2015","journal-title":"Sex Transm Infect"},{"key":"bibr12-0956462416649888","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ738"},{"key":"bibr13-0956462416649888","doi-asserted-by":"publisher","DOI":"10.3201\/eid0706.010603"},{"key":"bibr14-0956462416649888","volume-title":"Trichomonads parasitic in humans","author":"Rein M","year":"1990"},{"key":"bibr15-0956462416649888","unstructured":"Muir P. Economic evaluation of the Aptima TV TMA, http:\/\/public.ukcrn.org.uk\/search\/StudyDetail.aspx?StudyID=13827 (2013, accessed 20 February 2016)."},{"key":"bibr16-0956462416649888","doi-asserted-by":"crossref","first-page":"O06.1","DOI":"10.1136\/sextrans-2015-052126.188","volume":"91","author":"Nathan B","year":"2015","journal-title":"Sex Transm Infect"}],"container-title":["International Journal of STD & AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462416649888","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462416649888","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462416649888","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:36:10Z","timestamp":1777674970000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462416649888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,10]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1177\/0956462416649888"],"URL":"https:\/\/doi.org\/10.1177\/0956462416649888","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,10]]}}}