{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:39:07Z","timestamp":1777927147951,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T00:00:00Z","timestamp":1468108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:p>This cross-sectional study was undertaken to compare health-related quality of life (EQ-5D) in women with and without undiagnosed Chlamydia trachomatis infection. We analysed data from 2401 multi-ethnic sexually active female students aged 16\u201327 years who were recruited to a randomised controlled trial of chlamydia screening \u2013 the prevention of pelvic infection trial in 2004\u20132006. At recruitment, all participants were asked to provide self-taken vaginal swabs for chlamydia testing and to complete a sexual health questionnaire including quality of life (EQ-5D). Most women (69%) had an EQ-5D of one representing \u2018perfect health\u2019 in the five dimensions: mobility, self-care, usual activities, pain\/discomfort and anxiety\/depression. We therefore compared the proportion of women with an EQ-5D score\u2009&lt;\u20091 implying \u2018less than perfect health\u2019 in women with and without chlamydia infection, and women with symptomatic chlamydia versus the remainder. The proportion of women with EQ-5D score\u2009&lt;\u20091 was similar in women with and without undiagnosed chlamydia: 34% (47\/138) versus 31% (697\/2263; RR 1.11, 95% CI 0.87 to 1.41). However, more women with symptomatic chlamydia had EQ-5D score\u2009&lt;\u20091 than the remainder: 45% (25\/55) versus 31% (714\/2319; RR 1.47, CI 1.10 to 1.98). In this community-based study, EQ-5D scores were similar in women with and without undiagnosed chlamydia. However, a higher proportion of women with symptomatic chlamydia infection had \u2018less than perfect health\u2019. Undiagnosed chlamydia infection may not have a major short-term effect on health-related quality of life, but EQ-5D may not be the best tool to measure it in this group.<\/jats:p>","DOI":"10.1177\/0956462416650095","type":"journal-article","created":{"date-parts":[[2016,5,7]],"date-time":"2016-05-07T04:22:11Z","timestamp":1462594931000},"page":"367-371","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Health-related quality of life and\n                    <i>Chlamydia trachomatis<\/i>\n                    infection in sexually experienced female inner-city students: a community-based cross-sectional study"],"prefix":"10.1177","volume":"28","author":[{"given":"Trisha","family":"Sri","sequence":"first","affiliation":[{"name":"Population Health Research Institute, St George\u2019s University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleanor","family":"Southgate","sequence":"additional","affiliation":[{"name":"Population Health Research Institute, St George\u2019s University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah R","family":"Kerry","sequence":"additional","affiliation":[{"name":"Population Health Research Institute, St George\u2019s University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Nightingale","sequence":"additional","affiliation":[{"name":"Queen Mary University of London, Centre for Primary Care and Public Health, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pippa","family":"Oakeshott","sequence":"additional","affiliation":[{"name":"Population Health Research Institute, St George\u2019s University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,10]]},"reference":[{"key":"bibr1-0956462416650095","volume-title":"Chlamydia control in Europe: literature review","author":"European Centre for Disease Prevention and Control","year":"2014"},{"key":"bibr2-0956462416650095","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c1642"},{"key":"bibr3-0956462416650095","volume-title":"Guide to methods of technology appraisal. PMG9","author":"NICE","year":"2013"},{"key":"bibr4-0956462416650095","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.322.7280.195"},{"key":"bibr5-0956462416650095","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cml031"},{"key":"bibr6-0956462416650095","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2014-051677"},{"key":"bibr7-0956462416650095","volume-title":"Vaccines for the 21st century: a tool for decision making","author":"Institute of Medicine","year":"1999"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462416650095","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462416650095","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462416650095","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:36:10Z","timestamp":1777674970000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462416650095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,10]]},"references-count":7,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1177\/0956462416650095"],"URL":"https:\/\/doi.org\/10.1177\/0956462416650095","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,10]]}}}