{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:39:30Z","timestamp":1777927170063,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2017,1,6]],"date-time":"2017-01-06T00:00:00Z","timestamp":1483660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>It is recognised that those diagnosed with HIV infection over the age of 50 have higher rates of morbidity and mortality. Little is known about how clinical presentation at diagnosis of HIV varies within this group. We sought to compare clinical presentation and markers of outcome among those diagnosed with HIV aged 60 and over vs. those diagnosed aged 50\u201359, over a ten-year period. The results showed that 84\/111 were diagnosed with HIV aged 50\u201359 and 27\/111 aged \u226560. Ethnicity and HIV risk factors were similar between groups, and most infections were sexually acquired with 7.4% of those aged \u226560 suspected to have a recent infection. Median CD4 cell count at presentation was significantly lower in the \u226560 age group (111 vs. 249; p\u2009&lt;\u20090.001), and the proportion with a CD4 cell count &lt;50 was also significantly lower in this population (33% vs. 15%; p\u2009=\u20090.04). In keeping with this, the frequency of AIDS-defining illness at diagnosis was higher in the \u226560 group (38% vs. 4%; p\u2009&lt;\u20090.001). Co-morbidities were found in both groups, and 38% of those aged \u226560 at diagnosis were known to have since died compared to 4% of those aged 50\u201359 at diagnosis ( p\u2009\u2264\u20090.01). Those aged \u226560 had lower CD4 cell counts at diagnosis and more AIDS-defining illnesses, highlighting the increased risk of poor outcomes in this group. The majority of infections were sexually acquired. More work is needed to understand survival in adults diagnosed with HIV at an older age and to consider those over 60 as a specific population worthy of further research.<\/jats:p>","DOI":"10.1177\/0956462416685891","type":"journal-article","created":{"date-parts":[[2017,1,7]],"date-time":"2017-01-07T11:09:38Z","timestamp":1483787378000},"page":"1028-1033","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["HIV diagnosis in older adults"],"prefix":"10.1177","volume":"28","author":[{"given":"Rebecca","family":"Metcalfe","sequence":"first","affiliation":[{"name":"Sandyford Sexual Health Service, NHS Greater Glasgow & Clyde, Glasgow, UK"},{"name":"Gartnavel General Hospital, NHS Greater Glasgow & Clyde, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joe","family":"Schofield","sequence":"additional","affiliation":[{"name":"Public Health Protection Unit, NHS Greater Glasgow & Clyde, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catriona","family":"Milosevic","sequence":"additional","affiliation":[{"name":"Public Health Protection Unit, NHS Greater Glasgow & Clyde, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seija","family":"Peters","sequence":"additional","affiliation":[{"name":"Gartnavel General Hospital, NHS Greater Glasgow & Clyde, Glasgow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,1,6]]},"reference":[{"key":"bibr1-0956462416685891","unstructured":"World Health Organisation. HIV data and statistics, www.who.int\/hiv\/data\/epi_core_dec2014.png?ua=1 (2013, accessed 17 March 2015)."},{"key":"bibr2-0956462416685891","unstructured":"Public Health England. HIV in the United Kingdom: 2013 report, www.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/326601\/HIV_annual_report_2013.pdf (accessed 17 March 2015)."},{"key":"bibr3-0956462416685891","unstructured":"Halve it. www.halveit.org.uk\/resources\/Halve_It_Position_Paper.pdf (2014, accessed 17 March 2015)."},{"key":"bibr4-0956462416685891","unstructured":"BASHH BHIVA BIS. UK National Guidelines for HIV Testing 2008, www.bhiva.org\/HIV-testing-guidelines.aspx (accessed 17 March 2015)."},{"key":"bibr5-0956462416685891","volume-title":"Revised recommendations for HIV testing of adults, adolescents, and pregnant women in Health-Care Settings","author":"Branson BM","year":"2006"},{"key":"bibr6-0956462416685891","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62035-8"},{"key":"bibr7-0956462416685891","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1994.00420010085010"},{"key":"bibr8-0956462416685891","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.83.10.1400"},{"key":"bibr9-0956462416685891","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-13-397"},{"key":"bibr10-0956462416685891","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.12070"},{"key":"bibr11-0956462416685891","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32833c7b9c"},{"key":"bibr12-0956462416685891","doi-asserted-by":"publisher","DOI":"10.1177\/0898264314538664"},{"key":"bibr13-0956462416685891","unstructured":"Public Health England. HIV in the UK \u2013 Situation Report 2015 incidence, prevalence and prevention, www.gov.uk\/government\/statistics\/hiv-in-the-united-kingdom (accessed 21 October 2016)."},{"key":"bibr14-0956462416685891","doi-asserted-by":"publisher","DOI":"10.1177\/0956462415589524"},{"key":"bibr15-0956462416685891","unstructured":"National Records of Scotland. www.nrscotland.gov.uk\/statistics-and-data\/statistics\/stats-at-a-glance\/council-area-profiles (accessed 10 November 2016)."}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462416685891","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462416685891","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462416685891","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:36:47Z","timestamp":1777675007000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462416685891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,6]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1177\/0956462416685891"],"URL":"https:\/\/doi.org\/10.1177\/0956462416685891","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,6]]}}}