{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:28:03Z","timestamp":1787502483595,"version":"build-2736575974"},"reference-count":47,"publisher":"SAGE Publications","issue":"13","license":[{"start":{"date-parts":[[2017,4,14]],"date-time":"2017-04-14T00:00:00Z","timestamp":1492128000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:p>We compared the prevalence of menopause symptoms between women living with HIV to their HIV-negative peers and determined predictors of severe menopause symptoms in Jos, Nigeria. This descriptive cross-sectional study included 714 women aged 40\u201380 years. We compared prevalence and severity of menopause symptoms using the menopause rating scale (MRS). Logistic regression analysis was used to determine the predictors of severe symptoms. Six-hundred and seven (85.0%) were HIV-positive, with a mean duration of infection of 5.6\u2009\u00b1\u20092.7 years. The mean age of the cohort was 46\u2009\u00b1\u20095 years. The most prevalent menopause symptoms were hot flushes (67.2%), joint and muscle discomfort (66.2%), physical\/mental exhaustion (65.3%), heart discomfort (60.4%), and anxiety (56.4%). The median MRS score was higher for HIV-positive compared to HIV-negative women (p\u2009=\u20090.01). Factors associated with severe menopause symptoms included HIV-positive status (aOR: 3.01, 95% CI: 1.20\u20137.54) and history of cigarette smoking (aOR: 4.18, 95% CI: 1.31\u201313.26). Being married (aOR: 0.49, 95% CI: 0.32\u20130.77), premenopausal (aOR: 0.60, 95% CI: 0.39\u20130.94), and self-reporting good quality of life (aOR: 0.62. 95% CI: 0.39\u20130.98) were protective against severe menopause symptoms. We found HIV infection, cigarette smoking, quality of life, and stage of the menopause transition to be associated with severe menopause symptoms. As HIV-positive populations are aging, additional attention should be given to the reproductive health of these women.<\/jats:p>","DOI":"10.1177\/0956462417704778","type":"journal-article","created":{"date-parts":[[2017,4,14]],"date-time":"2017-04-14T07:03:40Z","timestamp":1492153420000},"page":"1325-1334","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Prevalence and predictors of severe menopause symptoms among HIV-positive and -negative Nigerian women"],"prefix":"10.1177","volume":"28","author":[{"given":"Patricia A","family":"Agaba","sequence":"first","affiliation":[{"name":"Department of Family Medicine, University of Jos\/Jos University Teaching Hospital, Jos, Nigeria"},{"name":"APIN Centre, Jos University Teaching Hospital, Jos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema T","family":"Meloni","sequence":"additional","affiliation":[{"name":"Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halima M","family":"Sule","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, University of Jos\/Jos University Teaching Hospital, Jos, Nigeria"},{"name":"APIN Centre, Jos University Teaching Hospital, Jos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amaka N","family":"Ocheke","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynaecology, University of Jos\/Jos University Teaching Hospital, Jos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel I","family":"Agaba","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Jos\/Jos University Teaching Hospital, Jos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A","family":"Idoko","sequence":"additional","affiliation":[{"name":"National Agency for the Control of AIDS, Abuja, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phyllis J","family":"Kanki","sequence":"additional","affiliation":[{"name":"Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,4,14]]},"reference":[{"key":"bibr1-0956462417704778","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S2497"},{"key":"bibr2-0956462417704778","doi-asserted-by":"publisher","DOI":"10.4103\/2278-960X.153516"},{"key":"bibr3-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1136\/jfprhc.2010.0015"},{"key":"bibr4-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0b013e3182886093"},{"key":"bibr5-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2014.4863"},{"key":"bibr6-0956462417704778","first-page":"OC08","volume":"9","author":"Sekhar TV","year":"2015","journal-title":"J Clin Diagn Res"},{"key":"bibr7-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000000416"},{"key":"bibr8-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2016.01.005"},{"key":"bibr9-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1086\/497270"},{"key":"bibr10-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2005.19.703"},{"key":"bibr11-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e31824cfc0f"},{"key":"bibr12-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2013.07.012"},{"key":"bibr13-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1097\/01.GME.0000141981.88782.38"},{"key":"bibr14-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e31815879df"},{"key":"bibr15-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1080\/09513590701253743"},{"key":"bibr16-0956462417704778","unstructured":"UNAIDS. HIV and aging: a special supplement to the UNAIDS report on the global AIDS epidemic. Geneva: Joint UN Programme on HIV\/AIDS, http:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/20131101_JC2563_hiv-and-aging_en_0.pdf (2013, accessed 20 April 2015)."},{"key":"bibr17-0956462417704778","unstructured":"WHO, UNICEF and UNAIDS. Global AIDS response progress reporting 2013: construction of core indicators for monitoring the 2011 UN Political Declaration on HIV\/AIDS.\n                      A guide on indicators for the monitoring and reporting on the health sector response to HIV\/AIDS.\n                      Geneva: UNAIDS, http:\/\/www.unaids.org\/en\/media\/unaids\/contentassets\/documents\/document\/2013\/GARPR_2013_guidelines_en.pdf (2013, accessed 8 July 2015)."},{"key":"bibr18-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1186\/1742-6405-10-30"},{"key":"bibr19-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-015-0959-0"},{"key":"bibr20-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2012.01051.x"},{"key":"bibr21-0956462417704778","doi-asserted-by":"crossref","unstructured":"Cecilia B, Rosario R, Antonio B, et\u00a0al. Menopause in HIV infected women: a comprehensive approach to physical and psychological health.\n                      J Osteopor Phys Act\n                      2014; 2: 117.","DOI":"10.4172\/2329-9509.1000117"},{"key":"bibr22-0956462417704778","doi-asserted-by":"crossref","unstructured":"Ramakuela NJ, Akinsola HA, Khoza LB, et\u00a0al. Perceptions of menopause and aging in rural villages of Limpopo Province, South Africa.\n                      Health SA Gesondheid.\n                      2014; 19: Article #771. DOI: 10.4102\/hsag.v19i1.771.","DOI":"10.4102\/hsag.v19i1.771"},{"key":"bibr23-0956462417704778","doi-asserted-by":"crossref","unstructured":"Adewuyi TDO and Akinade EA. 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Psychological effects and experiences of menopausal women in a rural community in Niger Delta region of Nigeria.\n                      Int J Nurs Midwifery\n                      2014; 6: 74\u201379."},{"key":"bibr26-0956462417704778","doi-asserted-by":"publisher","DOI":"10.5539\/gjhs.v5n4p39"},{"key":"bibr27-0956462417704778","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2013.02.018"},{"key":"bibr28-0956462417704778","doi-asserted-by":"publisher","DOI":"10.4103\/0189-5117.199819"},{"key":"bibr29-0956462417704778","volume-title":"Research on menopause in the 1990s. 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