{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:39:49Z","timestamp":1777927189963,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T00:00:00Z","timestamp":1498694400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p>Pulmonary involvement in secondary syphilis is considered a rare occurrence; however, the number of cases has increased in the 2000s. This is likely due to the increased use of computed tomography scans and molecular diagnostic testing. We report a case of an HIV-positive man with pleural chest pain and bilateral subpleural nodules on chest computed tomography. His rapid plasma reagin and Treponema pallidum hemagglutination tests were positive, and the specimen of one of the pulmonary nodules obtained by transthoracic biopsy was positive for the polA gene of Treponema pallidum. Since clinical manifestations of syphilis are highly variable, clinicians should bear in mind that pleural chest pain with bilateral subpleural nodules can be caused by pulmonary syphilis.<\/jats:p>","DOI":"10.1177\/0956462417717653","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T10:09:53Z","timestamp":1498730993000},"page":"89-91","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Pulmonary involvement of secondary syphilis"],"prefix":"10.1177","volume":"29","author":[{"given":"Yoshihiko","family":"Ogawa","sequence":"first","affiliation":[{"name":"Center for Infectious Diseases, Nara Medical University, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichiro","family":"Imai","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, Nara Medical University, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Yoshihara","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, Nara Medical University, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Fujikura","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, Nara Medical University, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyasu","family":"Hirai","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, Nara Medical University, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masatoshi","family":"Sato","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Nara City Hospital, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taku","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, Nara Medical University, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Uno","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Minami Nara General Medical Center, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kei","family":"Kasahara","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, Nara Medical University, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisakazu","family":"Yano","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Infectious Diseases, Nara Medical University, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Mikasa","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, Nara Medical University, Nara, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,6,29]]},"reference":[{"key":"bibr1-0956462417717653","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.JJID.2015.312"},{"key":"bibr2-0956462417717653","doi-asserted-by":"publisher","DOI":"10.1086\/499104"},{"key":"bibr3-0956462417717653","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201511-2296IM"},{"key":"bibr4-0956462417717653","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13483"},{"key":"bibr5-0956462417717653","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0000000000000662"},{"key":"bibr6-0956462417717653","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2014.10.005"},{"key":"bibr7-0956462417717653","author":"Sprenger K","journal-title":"BMJ Case Rep"},{"key":"bibr8-0956462417717653","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2013.28.2.231"},{"key":"bibr9-0956462417717653","first-page":"409896","volume":"2012","author":"Elzouki AN","year":"2012","journal-title":"Case Rep Infect Dis"},{"key":"bibr10-0956462417717653","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-1100"},{"key":"bibr11-0956462417717653","doi-asserted-by":"publisher","DOI":"10.4103\/0971-3026.76052"},{"key":"bibr12-0956462417717653","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.091479"},{"key":"bibr13-0956462417717653","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.098178"},{"key":"bibr14-0956462417717653","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2015-210618","volume":"2015","author":"Crouzy F","year":"2015","journal-title":"BMJ Case Rep"},{"key":"bibr15-0956462417717653","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700888"},{"key":"bibr16-0956462417717653","first-page":"875","volume":"138","author":"Coleman DL","year":"1983","journal-title":"West J Med"}],"container-title":["International Journal of STD &amp; 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