{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T11:08:34Z","timestamp":1792408114820,"version":"4.4.0"},"reference-count":14,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T00:00:00Z","timestamp":1499990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:p>We assessed whether urethral microscopy was performed as per clinic protocol for male clinic attendees reporting contact with Neisseria gonorrhoeae (GC), urethral symptoms or given a diagnosis of epididymo-orchitis (EO) over a 12-month period (9732 patients). Prevalence of gonorrhoea in the contacts, urethral symptoms and EO groups was 50, 12.7 and 1.6%, respectively. Microscopy was performed reliably for contacts (96%), those with discharge\/dysuria with evidence of urethritis on examination (98%), but not those with EO (43%). We explored the clinical utility of microscopy as a point-of-care test for identifying urethral GC in each subgroup, using the APTIMA Combo 2 CT\/GC nucleic acid amplification test as the comparator (1710 patients). Sensitivity of microscopy for each subgroup was good; there was no statistical difference between subgroup sensitivity using Fisher\u2019s exact test. Microscopy is valuable to ensure prompt diagnosis and contact tracing. All GC contacts were treated \u2018epidemiologically\u2019; however, half of GC contacts did not have GC. Microscopy identified the majority of GC cases, including amongst contacts (71% of heterosexual contacts, 66% of contacts reporting sex with men). We propose that epidemiological treatment for GC contacts should be reconsidered on the grounds of antibiotic stewardship, favouring use of microscopy to guide treatment decisions.<\/jats:p>","DOI":"10.1177\/0956462417721062","type":"journal-article","created":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T11:11:31Z","timestamp":1500549091000},"page":"157-163","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Auditing the use and assessing the clinical utility of microscopy as a point-of-care test for\n                    <i>Neisseria gonorrhoeae<\/i>\n                    in a Sexual Health clinic"],"prefix":"10.1177","volume":"29","author":[{"given":"Sarah","family":"Mensforth","sequence":"first","affiliation":[{"name":"Department of Sexual Health, Whittall Street Clinic, University Hospitals Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Thorley","sequence":"additional","affiliation":[{"name":"Department of Sexual Health, Whittall Street Clinic, University Hospitals Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Radcliffe","sequence":"additional","affiliation":[{"name":"Department of Sexual Health, Whittall Street Clinic, University Hospitals Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,7,14]]},"reference":[{"key":"bibr1-0956462417721062","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2012-050656"},{"key":"bibr2-0956462417721062","doi-asserted-by":"publisher","DOI":"10.3310\/hta14290"},{"key":"bibr3-0956462417721062","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03461-12"},{"key":"bibr4-0956462417721062","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00806-13"},{"key":"bibr5-0956462417721062","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2013-051147"},{"key":"bibr6-0956462417721062","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-005322"},{"key":"bibr7-0956462417721062","first-page":"422","volume":"72","author":"Sherrard J","year":"1996","journal-title":"Genitourin Med"},{"key":"bibr8-0956462417721062","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2011.011267"},{"key":"bibr9-0956462417721062","unstructured":"Bignell C, Ison C and Fitzgerald M. Clinical Effectiveness Group, British Association for Sexual Health and HIV. United Kingdom National Guideline for Gonorrhoea Testing 2012, https:\/\/www.bashh.org\/documents\/4490.pdf (2012, accessed December 2016)."},{"key":"bibr10-0956462417721062","unstructured":"Aptima Combo 2 Assay Package Insert. San Diego, CA: Gen-Probe Incorporated, http:\/\/www.hologic.com\/sites\/default\/files\/package%20inserts\/502183EN-IFU-PI_004_01.pdf (accessed April 2017)."},{"key":"bibr11-0956462417721062","unstructured":"UK Standards for microbiology investigations. SMI TP39: staining procedures. London, UK: Public Health England, https:\/\/www.gov.uk\/government\/publications\/smi-tp-39-staining-procedures (July 2015, accessed December 2016)."},{"key":"bibr12-0956462417721062","doi-asserted-by":"publisher","DOI":"10.1177\/0956462415586675"},{"key":"bibr13-0956462417721062","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2011.011023"},{"key":"bibr14-0956462417721062","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01217-11"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462417721062","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462417721062","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462417721062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:37:22Z","timestamp":1777675042000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462417721062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,14]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1177\/0956462417721062"],"URL":"https:\/\/doi.org\/10.1177\/0956462417721062","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,14]]}}}