{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:19:10Z","timestamp":1791944350316,"version":"4.3.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2019,5,19]],"date-time":"2019-05-19T00:00:00Z","timestamp":1558224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>The use of immunosuppressive drugs predisposes to infections, as they block the most important stage in antiviral defense, which is the cytotoxic T-lymphocyte HLA-dependent response. We report a case of extensive genital warts in a young woman on therapy for psoriasis with cyclosporine, afterwards successfully treated with an anti-tumor necrosis factor alpha (TNF-\u03b1) agent. Cyclosporine may predispose to the reactivation of latent infections and may favor the clinical manifestations of human papillomavirus (HPV)-related diseases, due to the inhibition of cell-mediated immunity that plays a crucial role in controlling HPV infections. In the literature the relationship between HPV and TNF-blockers has not yet been clearly defined. Our case underlines that the prompt interruption of cyclosporine can induce a complete regression of warts without any additional treatment and adds evidence to the possible use of anti-TNF-\u03b1 in patients with psoriasis and genital warts.<\/jats:p>","DOI":"10.1177\/0956462419833218","type":"journal-article","created":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T01:23:00Z","timestamp":1558315380000},"page":"828-830","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of psoriasis treatment on genital warts: a case report"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3843-0108","authenticated-orcid":false,"given":"Marco","family":"Campoli","sequence":"first","affiliation":[{"name":"Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Cinotti","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Fimiani","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Pellegrino","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Tognetti","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Rubegni","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,5,19]]},"reference":[{"key":"bibr1-0956462419833218","doi-asserted-by":"publisher","DOI":"10.2174\/15665240113139990041"},{"key":"bibr2-0956462419833218","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(96)00153-4"},{"key":"bibr3-0956462419833218","first-page":"155","volume":"25","author":"Adamczyk M","year":"2017","journal-title":"Acta Dermatovenerol Croat"},{"key":"bibr4-0956462419833218","doi-asserted-by":"publisher","DOI":"10.1159\/000190319"},{"key":"bibr5-0956462419833218","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(08)81994-9"},{"key":"bibr6-0956462419833218","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70186-W"},{"key":"bibr7-0956462419833218","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2009.279"},{"key":"bibr8-0956462419833218","first-page":"9","volume":"18","author":"Georgala S","year":"2012","journal-title":"Dermatol Online J"},{"key":"bibr9-0956462419833218","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-014-3157-1"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462419833218","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462419833218","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462419833218","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:39:19Z","timestamp":1777675159000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462419833218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,19]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1177\/0956462419833218"],"URL":"https:\/\/doi.org\/10.1177\/0956462419833218","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,19]]}}}