{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T20:32:19Z","timestamp":1784752339231,"version":"3.55.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T00:00:00Z","timestamp":1569283200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>Anogenital warts, also known as condylomata acuminata caused by human papillomavirus constitute the most common sexually transmitted infection. Rarely, the disease may evolve into a huge cauliflower-like growth called giant condyloma acuminatum or Buschke\u2013L\u00f6wenstein tumor (BLT). In contrast with normal anogenital warts, BLT displays local invasion, lack of spontaneous resolution, posttreatment recurrence, and potential for malignant transformation. Although radical excision with split-thickness skin grafting is considered its first-line treatment, it is not always feasible. While many other treatments have shown variable success and recurrence rates, topical imiquimod 5%, a popular evidence-based therapy for warts has also been reported as an efficacious treatment for BLT. We present a case of penile BLT where the patient refused surgery but recovered completely with no recurrence at five years following 16 weeks\u2019 therapy with topical 5% imiquimod. Excepting a single reported case, this might be another case where BLT resolved with imiquimod as a standalone therapy. We also present a succinct review of past cases of BLT treated with imiquimod.<\/jats:p>","DOI":"10.1177\/0956462419855505","type":"journal-article","created":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T20:48:19Z","timestamp":1569358099000},"page":"1136-1139","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Successful nonsurgical treatment of penile Buschke\u2013L\u00f6wenstein tumor with 12 weeks of 5% imiquimod alone"],"prefix":"10.1177","volume":"30","author":[{"given":"Sidharth","family":"Sonthalia","sequence":"first","affiliation":[{"name":"SKINNOCENCE: The Skin Clinic & Research Centre, Gurugram, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Department of Dermatology and STD, UCMS & GTB Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5158-1317","authenticated-orcid":false,"given":"Mahima","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Dermatology and STD, LHMC & Associated Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Sharma","sequence":"additional","affiliation":[{"name":"Skin Institute & School of Dermatology (SISD), New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,9,24]]},"reference":[{"key":"bibr1-0956462419855505","doi-asserted-by":"publisher","DOI":"10.1007\/BF01728480"},{"key":"bibr2-0956462419855505","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2014.01.023"},{"key":"bibr3-0956462419855505","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962012000100018"},{"key":"bibr4-0956462419855505","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-11-231"},{"key":"bibr5-0956462419855505","doi-asserted-by":"publisher","DOI":"10.4081\/dr.2015.6134"},{"key":"bibr6-0956462419855505","doi-asserted-by":"publisher","DOI":"10.1016\/j.eucr.2016.02.003"},{"key":"bibr7-0956462419855505","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.02938.x"},{"key":"bibr8-0956462419855505","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2007.00233.x"},{"key":"bibr9-0956462419855505","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X18802143"},{"key":"bibr10-0956462419855505","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2018.04.007"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462419855505","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462419855505","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462419855505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:39:34Z","timestamp":1777675174000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462419855505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,24]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1177\/0956462419855505"],"URL":"https:\/\/doi.org\/10.1177\/0956462419855505","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,24]]}}}