{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:41:39Z","timestamp":1777927299647,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,1,28]],"date-time":"2020-01-28T00:00:00Z","timestamp":1580169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Kyoto University Research Fund for Young Scientists"},{"name":"JSPS KAKENHI","award":["Grant Number 19K19353"],"award-info":[{"award-number":["Grant Number 19K19353"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:p>The number of syphilis cases reported in Japan, transmitted mainly by heterosexual contact, has been increasing since 2014. However, Japan has not introduced partner services programmes, and it remains unclear whether contacts of patients with syphilis undergo testing. This study aimed to estimate the proportion of spouses of patients with syphilis who underwent syphilis testing. We retrospectively identified patients who had recently started syphilis treatment as well as their spouses from a Japanese claims database for employee health insurance plans, collected between 2010 and 2017. Spousal syphilis testing was defined as either a nontreponemal or treponemal test within three months after the index patient started treatment. We determined the proportion of spousal syphilis testing and analysed its associations with patient and spouse characteristics, and year of syphilis treatment. Of the 217 patients who were identified to have started syphilis treatment, 29 (13.3%) spouses underwent syphilis testing: 23\/182 (12.6%) among wives, and 6\/35 (17.1%) among husbands, of male and female index patients, respectively. Among wives aged &lt;45\u2009years, the proportion tested declined over time. Despite the rise in syphilis incidence, the proportion of spouses tested, including women of reproductive age, declined. In Japan, partner services programmes need to be implemented to control sexually transmitted infections.<\/jats:p>","DOI":"10.1177\/0956462419892779","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T01:51:46Z","timestamp":1580262706000},"page":"214-220","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Syphilis testing among spouses of patients with syphilis in Japan: an epidemiological study using an administrative claims database"],"prefix":"10.1177","volume":"31","author":[{"given":"Keisuke","family":"Matsubayashi","sequence":"first","affiliation":[{"name":"Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7477-4071","authenticated-orcid":false,"given":"Koji","family":"Kawakami","sequence":"additional","affiliation":[{"name":"Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,1,28]]},"reference":[{"key":"bibr1-0956462419892779","volume-title":"Sexually transmitted disease surveillance 2017","author":"Centers for Infectious Disease Control and Prevention","year":"2018"},{"key":"bibr2-0956462419892779","unstructured":"Public Health England. Sexually transmitted infections (STIs): annual data tables, https:\/\/www.gov.uk\/government\/statistics\/sexually-transmitted-infections-stis-annual-data-tables (2010, accessed 26 July 2019)."},{"key":"bibr3-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000768"},{"key":"bibr4-0956462419892779","unstructured":"National Institute of Infectious Diseases. Infectious disease annual report 2014, https:\/\/www.niid.go.jp\/niid\/ja\/allarticles\/surveillance\/2270-idwr\/nenpou\/6142-syulist2014.html (2015, accessed 26 September 2019) (in Japanese)."},{"key":"bibr5-0956462419892779","unstructured":"National Institute of Infectious Diseases. Summary of syphilis notifications in Japan, https:\/\/www.niid.go.jp\/niid\/images\/epi\/syphilis\/2018q4\/syphilis2018q4.pdf (2019, accessed 26 July 2019) (in Japanese)."},{"key":"bibr6-0956462419892779","first-page":"1","volume":"3","author":"Ferreira A","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr7-0956462419892779","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr6404a1","volume":"64","author":"Workowski KA","year":"2015","journal-title":"MMWR Recomm Rep"},{"key":"bibr8-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1177\/0956462415624059"},{"key":"bibr9-0956462419892779","unstructured":"Public Health Agency of Canada. Canadian guidelines on sexually transmitted infections: management and treatment of specific infections \u2013 syphilis, https:\/\/www.canada.ca\/en\/public-health\/services\/infectious-diseases\/sexual-health-sexually-transmitted-infections\/canadian-guidelines\/sexually-transmitted-infections\/canadian-guidelines-sexually-transmitted-infections-27.html (2016, accessed 26 July 2019)."},{"key":"bibr10-0956462419892779","unstructured":"Australasian Sexual Health Alliance. Australian STI management guidelines for use in primary care. Syphilis, http:\/\/sti.guidelines.org.au\/sexually-transmissible-infections\/syphilis (2018, accessed 26 July 2019)."},{"key":"bibr11-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000842"},{"key":"bibr12-0956462419892779","doi-asserted-by":"publisher","DOI":"10.2188\/jea.JE20090066"},{"key":"bibr13-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1186\/s40780-015-0016-5"},{"key":"bibr14-0956462419892779","unstructured":"Japanese Society for Sexually Transmitted Infections. STI diagnosis and treatment guidelines 2011.\n                      Japanese J Sex Transm Infect\n                      , http:\/\/jssti.umin.jp\/pdf\/guideline-2011.pdf (2011, accessed 26 July 2019) (in Japanese)."},{"key":"bibr15-0956462419892779","unstructured":"Japanese Society for Sexually Transmitted Infections. STI diagnosis and treatment guidelines 2016.\n                      Japanese J Sex Transm Infect\n                      , http:\/\/jssti.umin.jp\/pdf\/guideline-2016.pdf (2016, accessed 26 July 2019) (in Japanese)."},{"key":"bibr16-0956462419892779","volume-title":"WHO guidelines for the treatment of Treponema pallidum (syphilis)","author":"World Health Organization","year":"2016"},{"key":"bibr17-0956462419892779","unstructured":"Statistics Bureau, Ministry of Internal Affairs and Communications. Portal site of official statistics of Japan. https:\/\/www.e-stat.go.jp\/ (2019, accessed 26 September 2019) (in Japanese)."},{"key":"bibr18-0956462419892779","first-page":"171","volume":"64","author":"Kodama T","year":"2010","journal-title":"Acta Med"},{"key":"bibr19-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000583"},{"key":"bibr20-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000884"},{"key":"bibr21-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000951"},{"key":"bibr22-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1086\/432476"},{"key":"bibr23-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041681"},{"key":"bibr24-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38678.405370.7C"},{"key":"bibr25-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-200004000-00003"},{"key":"bibr26-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1177\/0956462416688158"},{"key":"bibr27-0956462419892779","unstructured":"Naruse H, Jindai K, Saito T. Fictional heroes take on real public health problems: Japan\u2019s use of manga and anime in health campaigns, https:\/\/blogs.bmj.com\/bmj\/2019\/06\/11\/fictional-heroes-take-on-real-public-health-problems-japans-use-of-manga-and-anime-in-health-campaigns\/ (2019, accessed 26 July 2019)."},{"key":"bibr28-0956462419892779","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2007.114777"},{"key":"bibr29-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e31821c390b"},{"key":"bibr30-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.23.3.26"},{"key":"bibr31-0956462419892779","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60987-2"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462419892779","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462419892779","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462419892779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:40:13Z","timestamp":1777675213000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462419892779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,28]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1177\/0956462419892779"],"URL":"https:\/\/doi.org\/10.1177\/0956462419892779","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,28]]}}}