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Secondary HIV central nervous system (CNS) escape refers to the rare independent replication of HIV RNA in the central nervous system despite peripheral viral suppression that occurs in the setting of a concomitant non-HIV infection. We describe here a young man with perinatal HIV infection considered a viral controller who developed secondary HIV CNS escape in the setting of a presumed fungal CNS infection.<\/jats:p>","DOI":"10.1177\/0956462420922452","type":"journal-article","created":{"date-parts":[[2020,6,13]],"date-time":"2020-06-13T05:22:14Z","timestamp":1592025734000},"page":"694-698","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A rare case of HIV CNS escape in a patient previously considered a viral controller"],"prefix":"10.1177","volume":"31","author":[{"given":"Jessica","family":"Magid-Bernstein","sequence":"first","affiliation":[{"name":"Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5730-7770","authenticated-orcid":false,"given":"Chu-Yueh","family":"Guo","sequence":"additional","affiliation":[{"name":"Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco,  CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicia C","family":"Chow","sequence":"additional","affiliation":[{"name":"Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco,  CA, USA"},{"name":"Department of Medicine, Division of Infectious Diseases, University of California, San Francisco,  CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran T","family":"Thakur","sequence":"additional","affiliation":[{"name":"Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,6,13]]},"reference":[{"key":"bibr1-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis326"},{"key":"bibr2-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1086\/319602"},{"key":"bibr3-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1080\/13550280802195367"},{"key":"bibr4-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1086\/313810"},{"key":"bibr5-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199804000-00007"},{"key":"bibr6-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.3.355"},{"key":"bibr7-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1086\/657342"},{"key":"bibr8-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-016-0448-1"},{"key":"bibr9-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328355e6b2"},{"key":"bibr10-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-015-0267-7"},{"key":"bibr11-0956462420922452","doi-asserted-by":"crossref","first-page":"e0143618","DOI":"10.1128\/JVI.01436-18","volume":"93","author":"Rosas-Umbert M","year":"2019","journal-title":"J Virol"},{"key":"bibr12-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32835cf235"},{"key":"bibr13-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1086\/378300"},{"key":"bibr14-0956462420922452","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.17.4.19745"},{"key":"bibr15-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu679"},{"key":"bibr16-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2014.0014"},{"key":"bibr17-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1258\/ijsa.2011.010507"},{"key":"bibr18-0956462420922452","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0184441"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462420922452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0956462420922452","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0956462420922452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:40:42Z","timestamp":1777675242000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0956462420922452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1177\/0956462420922452"],"URL":"https:\/\/doi.org\/10.1177\/0956462420922452","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6]]}}}