{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:42:09Z","timestamp":1777927329709,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T00:00:00Z","timestamp":1603670400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>The aim of this study was to examine the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) in patients with anogenital condylomata acuminata (CA) and their association with recurrence and squamous intraepithelial neoplasia development. We conducted a descriptive study in 95 patients that had undergone surgical treatment for CA. The descriptive data, disease characteristics, and pre-treatment peripheral inflammatory biomarkers (PIBs) were recorded retrospectively. All parameters were compared in those with recurrent and non-recurrent CA. All PIBs were significantly higher in patients with the greatest genital wart size of &gt;2\u2009cm in the squamous intraepithelial lesion (SIL) group. Human papillomavirus (HPV) types 16, 18, 31 and 33, known to carry high risk for anogenital cancer, were significantly related to higher SII. Greater wart size, high-grade squamous intraepithelial lesion (HSIL), and higher PLR and SII values were highly associated with recurrent disease (p\u2009=\u20090.003, 0.006, 0.005 and 0.000, respectively). Of all recurrences, 34.1% were explained by HSIL and increased PLR and SII values. The prediction of CA recurrence is important to determine those patients at high risk. PLR and SII can be used for risk analysis in selected patient groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0956462420950562","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T17:13:50Z","timestamp":1603818830000},"page":"1380-1388","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Peripheral inflammatory biomarkers as predictors of recurrence in surgically-treated anogenital condylomata acuminata patients"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9452-9276","authenticated-orcid":false,"given":"P","family":"Basim","sequence":"first","affiliation":[{"name":"Department of General Surgery, Medical Faculty, Medipol University, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Yuksel","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Medical Faculty, Medipol University, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,10,26]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/0956462413481527"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21892"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-836942"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.08.011"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1258\/jms.2009.009058"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S197349"},{"key":"e_1_3_2_8_2","first-page":"321","article-title":"Neutrophil-to-lymphocyte ratio. 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Pretreatment neutrophil:lymphocyte ratio as a prognostic factor in cervical carcinoma. Anticancer Res 2012; 32: 1555\u20131561.","journal-title":"Anticancer Res"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S197623"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-0442"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.24507"},{"key":"e_1_3_2_30_2","first-page":"213","article-title":"Neutrophil-to-lymphocyte ratio in inflammatory bowel disease \u2013 as a new predictor of disease severity","volume":"116","author":"Acarturk G","year":"2015","unstructured":"Acarturk G, Acay A, Demir K, et\u00a0al. Neutrophil-to-lymphocyte ratio in inflammatory bowel disease \u2013 as a new predictor of disease severity. 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