{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:42:40Z","timestamp":1777927360621,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"13","license":[{"start":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T00:00:00Z","timestamp":1625616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"NIH","award":["U01-AI018136"],"award-info":[{"award-number":["U01-AI018136"]}]},{"name":"NIH Fogarty training grant","award":["D43 TW010060"],"award-info":[{"award-number":["D43 TW010060"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>Sexually transmitted infections (STIs) remain a public health concern because of their interaction(s) with HIV. In the HPTN 052 study, STIs were evaluated in both HIV-positive index cases and their HIV-negative partners at enrollment and at yearly follow-up visits. Our definition for STI was based on any infection with Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis, or Trichomonas vaginalis. We used log-binomial regression models to identify factors associated with prevalent STIs. Generalized estimating equation models with the Poisson distribution were used to compare STI incidence between HIV-positive index cases and HIV-negative partners. 8.1% of the participants had STIs at enrollment. The prevalence of STIs (8.9 vs. 7.2) was higher in HIV-positive index cases than HIV-negative partners. Being female (prevalence ratio (PR) = 1.61; 95% CI: 1.20\u20132.16) or unmarried (PR = 1.92; 95% CI: 1.17\u20133.14) was associated with prevalent STIs. Compared to HIV-negative male partners, HIV-positive female index cases had a higher risk of STI acquisition (incidence rate ratio (IRR) = 2.25; 95% CI: 1.70\u20132.97). While we are implementing HIV prevention interventions for HIV-negative people, we should also intensify targeted STI prevention interventions, especially among HIV-positive women.<\/jats:p>","DOI":"10.1177\/09564624211030368","type":"journal-article","created":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T22:55:08Z","timestamp":1625698508000},"page":"1204-1211","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Sexually transmitted infections among HIV serodiscordant partners: A secondary analysis of HIV Prevention Trial Network 052"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4231-4553","authenticated-orcid":false,"given":"Maganizo B","family":"Chagomerana","sequence":"first","affiliation":[{"name":"UNC Project-Malawi, Lilongwe, Malawi"},{"name":"Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 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