{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:58:41Z","timestamp":1792634321390,"version":"4.5.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2021,8,14]],"date-time":"2021-08-14T00:00:00Z","timestamp":1628899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100007351","name":"Secretaria de Ciencia y Tecnica, Universidad de Buenos Aires","doi-asserted-by":"publisher","award":["UBACyT 20020150100223BA"],"award-info":[{"award-number":["UBACyT 20020150100223BA"]}],"id":[{"id":"10.13039\/501100007351","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007351","name":"Secretaria de Ciencia y Tecnica, Universidad de Buenos Aires","doi-asserted-by":"publisher","award":["UBACyT 20020190100357BA"],"award-info":[{"award-number":["UBACyT 20020190100357BA"]}],"id":[{"id":"10.13039\/501100007351","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chlamydia trachomatis (CT) can infect the anorectum producing various signs and symptoms. There is scarce literature regarding the differences between LGV and non-LGV CT anorectal manifestations. We compare the clinical spectrum of LGV and non-LGV infections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients over 18 years with presumptive infectious anorectal symptoms were examined in two healthcare centres in Buenos Aires. The patients were studied and treated according to current sexually transmitted infection guidelines. Anorectal swabs were collected to detect and genotype CT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A three-year-long study on 317 patients with anorectal symptoms showed 45.11% CT infection (85% LGV strains). Of 140 samples, 92 were sequenced: 80\/119 LGV (L2b 45%, L1 32.5% and L2 22.5%) and 12\/21 non-LGV. Older age and HIV+ status were significantly higher in the LGV group. Anal discharge, bleeding, severe proctitis and anal ulcers were more common in the LGV group. Multivariate logistic regression analysis revealed that HIV infection, anorectal bleeding and oro-anal sex are independent predictors of LGV infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with anorectal symptoms, LGV serovars predominate over non-LGV ones. Clinical manifestations are not pathognomonic of a specific biovar. If genotyping is not available, having clinical predictors may help to presume an LGV infection and define length of treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624211038384","type":"journal-article","created":{"date-parts":[[2021,8,14]],"date-time":"2021-08-14T11:48:02Z","timestamp":1628941682000},"page":"1318-1325","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Chlamydia trachomatis anorectal infections by LGV (L1, L2 and L2b) and non-LGV serotypes in symptomatic patients in Buenos Aires, Argentina"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7659-7956","authenticated-orcid":false,"given":"Luciana","family":"La Rosa","sequence":"first","affiliation":[{"name":"Divisi\u00f3n Cirug\u00eda, Centro Privado de Cirug\u00eda y Coloproctolog\u00eda, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Svidler L\u00f3pez","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n Cirug\u00eda, Hospital Juan A. Fern\u00e1ndez, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea C","family":"Entrocassi","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Farmacia y Bioqu\u00edmica, C\u00e1tedra de Microbiolog\u00eda Cl\u00ednica, Buenos Aires, Argentina"},{"name":"Universidad de Buenos Aires, Instituto de Investigaci\u00f3n en Fisiopatolog\u00eda y Bioqu\u00edmica Cl\u00ednica (INFIBIOC), Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deysi","family":"L\u00f3pez Aquino","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n Cirug\u00eda, Hospital Juan A. Fern\u00e1ndez, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dolores","family":"Caffarena","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n Cirug\u00eda, Centro Privado de Cirug\u00eda y Coloproctolog\u00eda, Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina A","family":"B\u00fcttner","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Farmacia y Bioqu\u00edmica, C\u00e1tedra de Microbiolog\u00eda Cl\u00ednica, Buenos Aires, Argentina"},{"name":"Universidad de Buenos Aires, Instituto de Investigaci\u00f3n en Fisiopatolog\u00eda y Bioqu\u00edmica Cl\u00ednica (INFIBIOC), Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda L","family":"Gallo Vaulet","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Farmacia y Bioqu\u00edmica, C\u00e1tedra de Microbiolog\u00eda Cl\u00ednica, Buenos Aires, Argentina"},{"name":"Universidad de Buenos Aires, Instituto de Investigaci\u00f3n en Fisiopatolog\u00eda y Bioqu\u00edmica Cl\u00ednica (INFIBIOC), Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Rodr\u00edguez Fermepin","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Farmacia y Bioqu\u00edmica, C\u00e1tedra de Microbiolog\u00eda Cl\u00ednica, Buenos Aires, Argentina"},{"name":"Universidad de Buenos Aires, Instituto de Investigaci\u00f3n en Fisiopatolog\u00eda y Bioqu\u00edmica Cl\u00ednica (INFIBIOC), Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,8,14]]},"reference":[{"key":"bibr1-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1177\/0956462415618837"},{"key":"bibr2-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1086\/423966"},{"key":"bibr3-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12256"},{"key":"bibr4-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ756"},{"key":"bibr5-09564624211038384","doi-asserted-by":"publisher","DOI":"10.3201\/eid2503.180600"},{"key":"bibr6-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1258\/095646207781147319"},{"key":"bibr7-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.31.5.1060-1065.1993"},{"key":"bibr8-09564624211038384","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr6404a1","volume":"64","author":"Frieden TR","year":"2015","journal-title":"MMWR Recomm Rep"},{"key":"bibr9-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1177\/0956462413516100"},{"key":"bibr10-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(20)30225-1"},{"key":"bibr11-09564624211038384","doi-asserted-by":"publisher","DOI":"10.3201\/eid1111.050821"},{"key":"bibr12-09564624211038384","doi-asserted-by":"publisher","DOI":"10.14745\/ccdr.v44i02a04"},{"key":"bibr13-09564624211038384","doi-asserted-by":"publisher","DOI":"10.2807\/ese.14.48.19428-en"},{"key":"bibr14-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2012-050915"},{"key":"bibr15-09564624211038384","doi-asserted-by":"publisher","DOI":"10.3201\/EID2201.141867"},{"key":"bibr16-09564624211038384","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.000781"},{"key":"bibr17-09564624211038384","volume-title":"Bolet\u00edn sobre VIH, sida e ITS en Argentina. 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