{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:43:12Z","timestamp":1777927392560,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T00:00:00Z","timestamp":1647648000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>HIV transmission through vertical route can be reduced to a large extent with combination of medical interventions. Apart from maternal HIV status several other epidemiological attributes determine this transmission dynamics. Objective: The objective of this study was to identify various associated factors that determine and modify the risk of HIV transmission from a mother living with HIV to her child. Materials and method: A retrospective cohort-study was conducted with 518 HIV-positive pregnant women with delivering live babies between April 2016 \u2013 September 2018. The HIV status of the children was ascertained with polymerase chain reaction. A number of socio-demographic and medical attributes were compared between HIV-positive (41) and HIV-negative babies (477) using bivariate and multivariate methods to identify disease modifying factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Maternal HIV detection during the postnatal period (AOR = 11.2; 5.2 \u2013 23.8), low birth weight (AOR = 2.7; 1.2 \u2013 5.9), and vaginal delivery (AOR = 2.8; 1.01 \u2013 7.7) were significantly associated with vertical transmission of HIV. Lower duration of maternal antiretroviral treatment and higher maternal age (&gt;25\u00a0years) were also associated in bivariate analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The battery of PPTCT (Prevention of Parent to Child Transmission) interventions should be tailored in such a way to address all the epidemiological attributes influencing vertical transmission.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624221076618","type":"journal-article","created":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T04:22:07Z","timestamp":1647663727000},"page":"472-478","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Epidemiological drivers of mother to child HIV transmission in West Bengal, India: A retrospective cohort study"],"prefix":"10.1177","volume":"33","author":[{"given":"Suman","family":"Ganguly","sequence":"first","affiliation":[{"name":"West Bengal State AIDS Prevention & Control Society Kolkata, National AIDS Control Organisation, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3439-7475","authenticated-orcid":false,"given":"Debjit","family":"Chakraborty","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, ICMR- National Institute of Cholera and Enteric Disease, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Falguni","family":"Debnath","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, ICMR- National Institute of Cholera and Enteric Disease, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subrata","family":"Biswas","sequence":"additional","affiliation":[{"name":"Division of 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