{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:43:15Z","timestamp":1777927395797,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>\n                    We report here a case of alopecia probably caused by the fixed dose combination of doravirine\/tenofovir disproxil fumarate\/lamivudine (DOR\/TDF\/3TC) in a 46-year-old male living with HIV, previously treated with tenofovir disproxil fumarate and lamivudine-containing antiretroviral combinations. After having excluded other causes of hair loss such as sexually transmitted disease or drugs associated with alopecia, as well as poor immune-virologic conditions (i.e. low CD4\n                    <jats:sup>+<\/jats:sup>\n                    cell count and\/or high HIV viral load), a toxic effect of doravirine might be hypothesized. DOR\/TDF\/3TC was immediately stopped and rilpivirine plus tenofovir alafenamide fumarate\/emtricitabine was started. Four weeks after changing the antiretroviral regimen, the patient reported signs of hypopigmented hair regrowth. The association between the episode of alopecia and DOR\/TDF\/3TC was scored as probable according to the Naranjo causality scale. We concluded that alopecia was probably related to DOR but whether it is self-limiting, cannot be predicted at this stage.\n                  <\/jats:p>","DOI":"10.1177\/09564624221096299","type":"journal-article","created":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T02:25:23Z","timestamp":1651458323000},"page":"726-727","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Doravirine\/tenofovir disoproxyl fumarate\/lamivudine-induced alopecia: A case report"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1512-6530","authenticated-orcid":false,"given":"Dario","family":"Cattaneo","sequence":"first","affiliation":[{"name":"Gestione Ambulatoriale Politerapie (GAP) Outpatient Clinic, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy"},{"name":"Unit of Clinical Pharmacology, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agostino","family":"Riva","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Poloni","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgia","family":"Carrozzo","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4922-6495","authenticated-orcid":false,"given":"Cristina","family":"Gervasoni","sequence":"additional","affiliation":[{"name":"Gestione Ambulatoriale Politerapie (GAP) Outpatient Clinic, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy"},{"name":"Department of Infectious Diseases, ASST Fatebenefratelli Sacco University Hospital, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,5,1]]},"reference":[{"key":"bibr1-09564624221096299","doi-asserted-by":"publisher","DOI":"10.1177\/1060028019869641"},{"key":"bibr2-09564624221096299","unstructured":"Doravirine-US Food and Drug Administration. Available at: https:\/\/www.fda.gov\/media\/128270\/download, (last access, January 1, 2022)."},{"key":"bibr3-09564624221096299","volume-title":"Prescribing Information","author":"Doravirine"},{"key":"bibr4-09564624221096299","doi-asserted-by":"publisher","DOI":"10.1177\/1060028014540451"},{"key":"bibr5-09564624221096299","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofz278"},{"key":"bibr6-09564624221096299","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2014.46.2.103"},{"key":"bibr7-09564624221096299","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0000000000000471"},{"key":"bibr8-09564624221096299","volume-title":"FDA Adverse Event Reporting System (FAERS)","author":"U.S. Food and Drug Administration"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624221096299","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624221096299","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624221096299","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:43:26Z","timestamp":1777675406000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624221096299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,1]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1177\/09564624221096299"],"URL":"https:\/\/doi.org\/10.1177\/09564624221096299","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,1]]}}}