{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:43:23Z","timestamp":1777927403551,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T00:00:00Z","timestamp":1660780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To describe risk factors\/incidence of abnormal cervical\/vaginal cytology\/histology and cancer among women living with human immunodeficiency virus (WLHIV) \u226565\u00a0years compared to HIV-negative matched controls<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cohort of patients who underwent Pap screening at the University of Maryland 01\/2003-04\/2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>WLHIV and HIV-negative controls ( n = 70 each) underwent 140\/151 Pap tests, respectively. Among WLHIV, 29% exhibited abnormal results and were less likely than HIV-negative women with normal Paps to have had serially negative Pap tests prior to age 65 ( p = .03). In both groups, 1.4% developed cervical cancer. Abnormal Paps were more frequent in WLHIV than in HIV-negative women (31% vs 10%, p &lt; .0001, RR:3.2, 95%CI1.9\u20135.4) as was HRHPV (high-risk human papillomavirus) status (43% vs 19%, p = .0233, RR:2.3, 95%CI1.2\u20134.6). The RR for an abnormal Pap was 2.6 (95% CI:1.1\u20134.2) for VL &gt;1000 copies\/mL and 0.4 (95% CI:0.2\u20130.7) for CD4 count of &gt;200 cells\/\u03bcL. No individual with an initially normal Pap experienced an abnormal result over a mean of 42.5 and 43.5\u00a0months in the HIV-positive and HIV-negative groups, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>HIV status was associated with a higher rate of abnormal Pap\/HRHPV; however, no significant difference in cervical\/vaginal cancer. Elevated VL\/low CD4 count were associated with greater risk for an abnormal Pap.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624221111280","type":"journal-article","created":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T13:02:55Z","timestamp":1660827775000},"page":"954-962","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Pap smear outcomes in elderly women living with HIV and HIV-negative matched controls"],"prefix":"10.1177","volume":"33","author":[{"given":"Kylie L","family":"Klein","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abby R","family":"Goron","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory H","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine, Evelyn Jordan Center, University of Maryland School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7098-6376","authenticated-orcid":false,"given":"Dana M","family":"Roque","sequence":"additional","affiliation":[{"name":"Division of Gynecologic Oncology, University of Maryland School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,8,18]]},"reference":[{"key":"bibr1-09564624221111280","unstructured":"Centers for Disease Control. HIV among people aged 50 and over. Available at: https:\/\/www.cdc.gov\/hiv\/group\/age\/olderamericans\/index.html (2019, accessed 29 November 2019)."},{"key":"bibr2-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000243"},{"issue":"4","key":"bibr3-09564624221111280","first-page":"591","volume":"84","author":"Wright TC","year":"1994","journal-title":"Obstet Gynecol"},{"key":"bibr4-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.8.1031"},{"key":"bibr5-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001765"},{"key":"bibr6-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.12.003"},{"key":"bibr7-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.18.1500"},{"key":"bibr8-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e31828177d7"},{"key":"bibr9-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200401020-00013"},{"key":"bibr10-09564624221111280","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21139"},{"key":"bibr11-09564624221111280","unstructured":"Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV. Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV. Centers for Disease Control and Prevention, National Institutes for Health, the HIV Medicine Association, and the Infectious Disease Society of America. Available at: https:\/\/clinicalinfo.hiv.gov\/en\/guidelines\/hiv-clinical-guidelines-adult-and-adolescent-opportunistic-infections\/human-0?view=full (accessed 20 Jul, 2022)."},{"key":"bibr12-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001707"},{"key":"bibr13-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-020-0920-9"},{"key":"bibr14-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22357"},{"key":"bibr15-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29913"},{"key":"bibr16-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70282-7"},{"key":"bibr17-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1111\/jog.13225"},{"key":"bibr18-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13207"},{"key":"bibr19-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.16.2120"},{"key":"bibr20-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0b013e3181585870"},{"key":"bibr21-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3182883a34"},{"key":"bibr22-09564624221111280","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21654"},{"key":"bibr23-09564624221111280","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"bibr24-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0000000000000435"},{"key":"bibr25-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0172548"},{"key":"bibr26-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28548"},{"key":"bibr27-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1016\/j.gore.2018.05.010"},{"key":"bibr28-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1177\/0969141315598174"},{"key":"bibr29-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2016.06.016"},{"key":"bibr30-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwu035"},{"key":"bibr31-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001585"},{"key":"bibr32-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-008-9118-9"},{"issue":"4","key":"bibr33-09564624221111280","first-page":"81","volume":"64","author":"Siddiqi AeA","year":"2015","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"bibr34-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0072142"},{"key":"bibr35-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agp034"},{"key":"bibr36-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0000000000000187"},{"key":"bibr37-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001708"},{"key":"bibr38-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001457"},{"key":"bibr39-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/2105061"},{"key":"bibr40-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001450"},{"key":"bibr41-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.12.1471"},{"key":"bibr42-09564624221111280","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.10.011"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624221111280","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624221111280","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624221111280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:43:38Z","timestamp":1777675418000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624221111280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,18]]},"references-count":42,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1177\/09564624221111280"],"URL":"https:\/\/doi.org\/10.1177\/09564624221111280","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,18]]}}}