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To increase access to STI testing, convenient approaches for sampling and testing are needed. We assessed the acceptability of self-collected vaginal swabs (SCVS) for STI testing among young women (16\u201324\u00a0years) attending a community-based sexual and reproductive health service in Zimbabwe.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A SCVS was used for point-of-care testing for\n                      <jats:italic toggle=\"yes\">Trichomonas vaginalis<\/jats:italic>\n                      and a urine sample for testing for\n                      <jats:italic toggle=\"yes\">Chlamydia trachomatis<\/jats:italic>\n                      and\n                      <jats:italic toggle=\"yes\">Neisseria gonorrhoeae<\/jats:italic>\n                      . A questionnaire was administered to investigate the acceptability of SCVS versus self-collected urine samples. In-depth interviews (IDIs) explored the experience of SCVS and reasons for sample collection preference. Qualitative analysis was predominantly deductive.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We recruited 129 women who took up STI testing (median age 20\u00a0years, IQR 18\u201322\u00a0years) and conducted 12 IDIs. Most participants reported that they understood the instructions (93.0%) and found SCVS easy (90.7%). Many participants felt relaxed (93.0%), in control (88.4%) and that they had enough privacy (90.7%). Pain or discomfort were reported by 16.3% and embarrassment by 15.5%. Among the 92 (71.3%) participants who provided both a SCVS and urine sample, 60.9% preferred SCVS. Sample collection method preferences were similar between 16\u201319 and 20\u201324year-olds. In IDIs, clear instructions, privacy, trust in the service and same-day results were perceived as important facilitators to taking up SCVS. Participants frequently described feeling relaxed and confident whilst taking a SCVS. Pain and discomfort were uncommon experiences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>SCVS for STI testing are acceptable to young women and a feasible method of sample collection in community-based settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624231152804","type":"journal-article","created":{"date-parts":[[2023,3,25]],"date-time":"2023-03-25T00:56:01Z","timestamp":1679705761000},"page":"574-580","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Acceptability of self-collected vaginal swabs for sexually transmitted infection testing among youth in a community-based setting in Zimbabwe"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5884-0203","authenticated-orcid":false,"given":"Helena","family":"Rochford","sequence":"first","affiliation":[{"name":"Biomedical Research and Training Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leyla","family":"Larsson","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4897-458X","authenticated-orcid":false,"given":"Victoria","family":"Simms","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"},{"name":"London School of Hygiene & Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constancia","family":"Mavodza","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"},{"name":"London School of Hygiene & Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lovemore","family":"Sigwadhi","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ethel","family":"Dauya","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Machiha","sequence":"additional","affiliation":[{"name":"Ministry of Health and Child Care"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell","family":"Mavhura","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatenda","family":"Bipiti","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chido","family":"Mangena","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0066-8345","authenticated-orcid":false,"given":"Tsitsi","family":"Bandason","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rashida A","family":"Ferrand","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"},{"name":"London School of Hygiene & Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanna C","family":"Francis","sequence":"additional","affiliation":[{"name":"London School of Hygiene & Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chido Dziva","family":"Chikwari","sequence":"additional","affiliation":[{"name":"Biomedical Research and Training Institute"},{"name":"London School of Hygiene & Tropical Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,3,24]]},"reference":[{"key":"e_1_3_4_2_2","volume-title":"Global progress report on HIV, viral hepatitis and sexually transmitted infections","author":"World Health Organization","year":"2021","unstructured":"World Health Organization. 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