{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:45:18Z","timestamp":1777927518976,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The UK pledged commitment to the global strategy of zero new HIV infections and HIV-related deaths by 2030. PrEP was commissioned in England in 2020 and is fundamental to achieving these targets, yet awareness and uptake are suboptimal in certain populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Sexual Health London (SHL) incorporated questions on its e-triage questionnaire estimating need for PrEP amongst online service users. Two types of signposting messaging were shown to users directing them to more detailed online content: PrEP-discussion (potential need) and PrEP-eligible (assumed need). The effectiveness of this signposting was evaluated by reviewing demographics and triage responses in returning users.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>426,149 SHL users requested STI screening between 1.7.21-31.10.22. 16% (69,867\/426,149) and 32.2% (137,489\/426,149) of individuals received PrEP-eligible and PrEP-discussion signposting. The PrEP-eligible cohort were: 41.0% gay\/bisexual or other men who have sex with men (GBMSM), 16.3% heterosexual males, 33.1% heterosexual females, and 60.6% were of white ethnicity. The PrEP-discussion cohort were: 9.3% GBMSM, 34.3%% heterosexual males, 45.5% heterosexual females and 63.7% of white ethnicity. 50.4% (35,190\/69,867) and 41.3% (56,808\/137,489) of the PrEP-eligible and PrEP discussion cohorts ordered a subsequent SHL STI testing kit, during which 10.0% (3510\/35,190) and 5.9% (3364\/56,808) reported taking PrEP. Of those who denied taking PrEP, 59% (18,702\/31,680) and 61.0% (32,559\/53,444) triggered PrEP signposting again. 95.4% of PrEP starters were GBMSM (6562\/6874) and 1.4% (97\/6874) heterosexual males\/females.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The e-service demonstrated feasibility in estimating PrEP need and signposting service users. Up to 16% of returning users subsequently commenced PrEP. This highlights significant missed opportunities for the remaining online users, who continue to report HIV acquisition risk(s). Further efforts regionally\/nationally to optimise uptake of PrEP, particularly among under-represented groups are warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624241231630","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T13:04:41Z","timestamp":1706792681000},"page":"471-476","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Improving awareness and uptake of pre-exposure HIV prophylaxis amongst service users accessing Sexual Health London, a regional online postal sexually transmitted infection testing health service"],"prefix":"10.1177","volume":"35","author":[{"given":"Curran","family":"Caoimhe","sequence":"first","affiliation":[{"name":"Chelsea and Westminster Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Spate","sequence":"additional","affiliation":[{"name":"Preventx Ltd, Sheffield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6457-3877","authenticated-orcid":false,"given":"Sara","family":"Day","sequence":"additional","affiliation":[{"name":"Chelsea and Westminster Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,1]]},"reference":[{"key":"bibr1-09564624241231630","volume-title":"England on track to end new HIV transmissions by 2030 [Internet]","author":"Department of Health and Social Care","year":"2023"},{"key":"bibr2-09564624241231630","volume-title":"Towards Zero - An action plan towards ending HIV transmission, AIDS and HIV-related deaths in England - 2022 to 2025 [Internet]","author":"Department of Health and Social Care","year":"2021"},{"key":"bibr3-09564624241231630","volume-title":"BHIVA\/BASHH guidelines on the use of HIV pre-exposure prophylaxis (PrEP) 2018 [Internet]","author":"British HIV Association","year":"2018"},{"key":"bibr4-09564624241231630","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2020-054732"},{"key":"bibr5-09564624241231630","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2020-054457"},{"key":"bibr6-09564624241231630","volume-title":"Reducing sexually transmitted infections [Internet]","author":"NICE"},{"key":"bibr7-09564624241231630","volume-title":"The annual official statistics data release [data to end of December 2021","author":"Lester J","year":"2022"},{"key":"bibr8-09564624241231630","volume-title":"HIV pre-exposure prophylaxis (PrEP) need and use in England data tables [Internet]","author":"UK Health Security Agency","year":"2022"},{"key":"bibr9-09564624241231630","volume-title":"Increasing uptake of PrEP in under-served groups [internet]","author":"Aston S","year":"2023"},{"key":"bibr10-09564624241231630","volume-title":"Not PrEPared: barriers to accessing HIV prevention drugs in England [internet]","author":"National AIDS Trust","year":"2022"},{"key":"bibr11-09564624241231630","doi-asserted-by":"publisher","DOI":"10.1590\/0034-7167-2021-0963"},{"key":"bibr12-09564624241231630","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2022.01.038"},{"key":"bibr13-09564624241231630","doi-asserted-by":"publisher","DOI":"10.2196\/20187"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241231630","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624241231630","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241231630","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:45:24Z","timestamp":1777675524000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624241231630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,1]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1177\/09564624241231630"],"URL":"https:\/\/doi.org\/10.1177\/09564624241231630","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,1]]}}}