{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:44:27Z","timestamp":1777927467360,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000380","name":"Guy's & St Thomas' Foundation","doi-asserted-by":"publisher","award":["EIC180702"],"award-info":[{"award-number":["EIC180702"]}],"id":[{"id":"10.13039\/501100000380","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000864","name":"British HIV Association","doi-asserted-by":"publisher","award":["Research award to Laura Cechin"],"award-info":[{"award-number":["Research award to Laura Cechin"]}],"id":[{"id":"10.13039\/501100000864","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MC_PC_17164"],"award-info":[{"award-number":["MC_PC_17164"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Synnovis","award":["Innovation Accelerator Fund"],"award-info":[{"award-number":["Innovation Accelerator Fund"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There are no validated waist circumference (WC) cut-offs to define metabolic syndrome in Black people with HIV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Cross-sectional analyses within the CKD-AFRICA study. We used Pearson correlation coefficients and receiver operating characteristic (ROC) curves to describe the relationship between WC and cardiometabolic parameters including triglycerides, cholesterol, glucose, glycated haemoglobin (HbA1c), and homeostatic model assessment for insulin resistance (HOMA-IR), and to identify optimal WC cut-offs for each of these outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We included 383 participants (55% female, median age 52\u00a0years) with generally well controlled HIV. Female and male participants had similar WC (median 98 vs. 97\u00a0cm, p = .16). Generally weak correlations (r\n                      <jats:sup>2<\/jats:sup>\n                      &lt; 0.2) between WC and other cardiometabolic parameters were observed, with low (&lt;0.7) areas under the ROC curves. The optimal WC cut-offs for constituents of the metabolic syndrome, HbA1c and HOMA-IR ranged from 92 to 101\u00a0cm in women and 89-98\u00a0cm in men, respectively; these cut-offs had variable sensitivity (52%\u2013100%) and generally poor specificity (28%\u201372%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this cohort of Black people with HIV, WC cut-offs for cardiometabolic risk factors in male participants were in line with the recommended value of 94\u00a0cm while in female participants they vastly exceeded the recommended 80\u00a0cm for white women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624241233036","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T14:12:21Z","timestamp":1708438341000},"page":"521-526","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Waist circumference and cardiometabolic parameters in people of African\/Caribbean ancestry with HIV in South London (CKD-AFRICA study)"],"prefix":"10.1177","volume":"35","author":[{"given":"Laura","family":"Cechin","sequence":"first","affiliation":[{"name":"King\u2019s College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lourdes","family":"Dominguez-Dominguez","sequence":"additional","affiliation":[{"name":"King\u2019s College Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucy","family":"Campbell","sequence":"additional","affiliation":[{"name":"King\u2019s College Hospital NHS Foundation Trust, London, UK"},{"name":"King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Hamzah","sequence":"additional","affiliation":[{"name":"St George\u2019s Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Fox","sequence":"additional","affiliation":[{"name":"King\u2019s College London, London, UK"},{"name":"Guys and St Thomas\u2019s NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Royce P","family":"Vincent","sequence":"additional","affiliation":[{"name":"King\u2019s College Hospital NHS Foundation Trust, London, UK"},{"name":"King\u2019s College London, London, UK"},{"name":"Synnovis Analytics, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios K","family":"Dimitriadis","sequence":"additional","affiliation":[{"name":"King\u2019s College Hospital NHS Foundation Trust, London, UK"},{"name":"King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Goff","sequence":"additional","affiliation":[{"name":"Leicester General Hospital, University of Leicester, Leicester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2844-1612","authenticated-orcid":false,"given":"Frank A","family":"Post","sequence":"additional","affiliation":[{"name":"King\u2019s College Hospital NHS Foundation Trust, London, UK"},{"name":"King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,20]]},"reference":[{"key":"bibr1-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192644"},{"key":"bibr2-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.201"},{"key":"bibr3-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2007.92"},{"key":"bibr4-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1093\/pubmed\/fdu115"},{"key":"bibr5-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0048883"},{"key":"bibr6-09564624241233036","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-1921"},{"key":"bibr7-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2018-001057"},{"key":"bibr8-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.13413"},{"key":"bibr9-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(20)30241-1"},{"key":"bibr10-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofy201"},{"key":"bibr11-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183029"},{"key":"bibr12-09564624241233036","unstructured":"Dominguez-Dominguez L, Campbell L, Barbini B, et al. Associations between social determinants of health and co- and multi-morbidity in people of Black ethnicities with HIV. in press."},{"key":"bibr13-09564624241233036","volume-title":"HOMA Calculator"},{"key":"bibr14-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2102953"},{"key":"bibr15-09564624241233036","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S88893"},{"key":"bibr16-09564624241233036","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofw174"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241233036","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624241233036","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241233036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:45:25Z","timestamp":1777675525000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624241233036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,20]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1177\/09564624241233036"],"URL":"https:\/\/doi.org\/10.1177\/09564624241233036","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,20]]}}}