{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:45:12Z","timestamp":1777927512743,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T00:00:00Z","timestamp":1711497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Possible resistance to recommended treatments for scabies has emerged recently. In response to anecdotal reports of a recent increase in treatment failure with permethrin, the British Association for Sexual Health and HIV (BASHH) released a statement alerting members to this.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To examine attendances and the treatment pathways for scabies cases seen at local sexual health clinics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>A case note review of scabies attendances between January 2017 and December 2023 was conducted. Data collected included patient demographics, clinical information, and scabies treatment histories. Statistical analysis was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>143 patients attended with scabies. The number of scabies cases did not appear to increase significantly from 2017 to 2023 ( p = .09). There was significant increase in median number of treatments per case per year over time ( p = .013). The number of individuals needing second-line treatments increased significantly over time ( p-trend &lt; 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Individuals with scabies are requiring more treatments to clear infection. Use of ivermectin has risen in the last year suggesting that second-line treatment is increasingly needed for eradication. Whilst treatment failure may be due to non-compliance with treatment and decontamination efforts for both index and contacts, the more recent change in findings could be attributed to a fall in permethrin efficacy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624241242167","type":"journal-article","created":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T12:45:50Z","timestamp":1711543550000},"page":"616-619","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Scratching beneath the surface: An evaluation of the management of scabies 2017\u20132023"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-5841-4806","authenticated-orcid":false,"given":"Bryony","family":"Broster","sequence":"first","affiliation":[{"name":"Brighton and Hove Sexual Health and Contraception Service, University Hospitals Sussex NHS Foundation Trust, Brighton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Clarke","sequence":"additional","affiliation":[{"name":"Brighton and Hove Sexual Health and Contraception Service, University Hospitals Sussex NHS Foundation Trust, Brighton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Collins","family":"Iwuji","sequence":"additional","affiliation":[{"name":"Brighton and Hove Sexual Health and Contraception Service, University Hospitals Sussex NHS Foundation Trust, Brighton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suneeta","family":"Soni","sequence":"additional","affiliation":[{"name":"Brighton and Hove Sexual Health and Contraception Service, University Hospitals Sussex NHS Foundation Trust, Brighton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,3,27]]},"reference":[{"key":"bibr1-09564624241242167","unstructured":"World Health Organisation. Scabies, https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/scabies (2023, accessed 23 August 2023)."},{"key":"bibr2-09564624241242167","unstructured":"Worth Health Organisation. Neglected tropical diseases, https:\/\/www.who.int\/health-topics\/neglected-tropical-diseases#tab=tab_1 (2023, accessed 23 August 2023)."},{"key":"bibr3-09564624241242167","unstructured":"Sashidahran PN, Basavaraj S, Bates CM, et al. 2016 UK national guideline on the management of scabies, https:\/\/www.bashhguidelines.org\/media\/1137\/scabies-2016.pdf (2016, accessed 24 August 2023)."},{"key":"bibr4-09564624241242167","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17339"},{"key":"bibr5-09564624241242167","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17538"},{"key":"bibr6-09564624241242167","unstructured":"Morris G, Haddow L. Possible increased incidence of scabies and treatment-resistant cases [email]. Message to: BASHH members 21 February 2023 (cited 05 September 2023)."},{"key":"bibr7-09564624241242167","unstructured":"World Health Organisation. Antimicrobial resistance, https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/antimicrobial-resistance (2021, accessed 31 October 2023)."},{"key":"bibr8-09564624241242167","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2023-055949"},{"key":"bibr9-09564624241242167","unstructured":"Rutland E. Possible increased incidence of scabies and treatment-resistant cases [email]. Message to: Broster, B 13 October 2023 (cited 31 October 2023)."}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241242167","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624241242167","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241242167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:45:31Z","timestamp":1777675531000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624241242167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,27]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1177\/09564624241242167"],"URL":"https:\/\/doi.org\/10.1177\/09564624241242167","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,27]]}}}