{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:44:27Z","timestamp":1777927467344,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:p>Receipt of nebulised pentamidine in people with HIV was audited to identify if individuals were appropriately receiving nebulised pentamidine, and whether national guidelines were being followed when prophylaxis was commenced and discontinued. Of 76 people with who received nebulised pentamidine, the main indication for starting nebulised pentamidine was a co-trimoxazole adverse drug reaction. Co-trimoxazole desensitization was not attempted before starting nebulised pentamidine. The main indication for stopping nebulised pentamidine prophylaxis was when immune reconstitution occurred. This single centre audit revealed that national guidelines were being followed in most cases. The lack of information regarding the reason for starting or stopping nebulised pentamidine prophylaxis, or detail of the clinician\u2019s concerns about potential poor adherence with oral regimens of prophylaxis as a reason for choosing nebulised pentamidine prophylaxis, identifies a need for improved documentation of clinicians\u2019 decision-making. Introduction of pharmacist-led interventions\/alerts using patients\u2019 electronic records, similar to those used in primary care, would enable the specialist pharmacy team to identify when and if co-trimoxazole desensitization has been offered and discussed\/declined before a clinician prescribes nebulised pentamidine as well as enabling identification of those in who pentamidine prophylaxis has been continued, despite \u201cimmune reconstitution\u201d.<\/jats:p>","DOI":"10.1177\/09564624241245155","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T04:06:15Z","timestamp":1712894775000},"page":"644-647","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Nebulised pentamidine prophylaxis of\n                    <i>pneumocystis<\/i>\n                    pneumonia in adults accessing HIV services at royal free hospital, London"],"prefix":"10.1177","volume":"35","author":[{"given":"Malin","family":"Bergstrom","sequence":"first","affiliation":[{"name":"HIV Services, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anika","family":"Rahim","sequence":"additional","affiliation":[{"name":"HIV Services, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Akodu","sequence":"additional","affiliation":[{"name":"HIV Services, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"},{"name":"Pharmacy Services, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin","family":"Marshall","sequence":"additional","affiliation":[{"name":"HIV Services, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"},{"name":"Pharmacy Services, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cora","family":"Harrison","sequence":"additional","affiliation":[{"name":"Medicine and Urgent Care, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louisa","family":"Penrose","sequence":"additional","affiliation":[{"name":"HIV Services, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc CI","family":"Lipman","sequence":"additional","affiliation":[{"name":"HIV Services, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"},{"name":"UCL Respiratory, Division of Medicine, University College London, London, UK"},{"name":"Respiratory Medicine, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2067-4291","authenticated-orcid":false,"given":"Robert F","family":"Miller","sequence":"additional","affiliation":[{"name":"HIV Services, Royal Free London NHS Foundation Trust, Royal Free Hospital, London, UK"},{"name":"Centre for Clinical Research in Infection and Sexual Health, Institute for Global Health, University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,4,12]]},"reference":[{"key":"bibr1-09564624241245155","volume-title":"Panel on Guidelines for the Prevention and treatment of opportunistic infections in adults and adolescents with HIV. 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