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In our case, a PLWH with recurrent locally advanced gastric cancer was treated with anti-PD-1 inhibitor and ART. A significant reduction in tumor lesions (as demonstrated by contrast-enhanced CT imaging) and a better quality of life were achieved following treatment. There have been limited studies on the treatment of PLWH with advanced gastric cancer. Chemotherapy is most often used, however, with unsatisfactory outcomes. to date, there have been no published reports on the use of PD-1 inhibitors in PLWH with advanced gastric cancer. Our report provides a valuable reference for future management of such patients.<\/jats:p>","DOI":"10.1177\/09564624241248676","type":"journal-article","created":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T23:17:40Z","timestamp":1713741460000},"page":"733-738","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Unusual presentation of PD-1 inhibitors in people living with HIV with advanced gastric cancer: Case report"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3206-3685","authenticated-orcid":false,"given":"Zhidi","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Oncology, Qingdao Branch of Shandong Public Health Clinical Center, Qingdao, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangyong","family":"XU","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Qingdao Branch of Shandong Public Health Clinical Center, Qingdao, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hiser Hospital Affiliated to Qingdao University, Shandong, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Oncology, Qingdao Branch of Shandong Public Health Clinical Center, Qingdao, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"YU","sequence":"additional","affiliation":[{"name":"Department of Oncology, Qingdao Branch of Shandong Public Health Clinical Center, Qingdao, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoni","family":"Wang","sequence":"additional","affiliation":[{"name":"Imaging Department, Qingdao Branch of Shandong Public Health Clinical Center, Qingdao, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,4,21]]},"reference":[{"key":"bibr1-09564624241248676","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dju503"},{"key":"bibr2-09564624241248676","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0000000000000327"},{"key":"bibr3-09564624241248676","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-018-4963-8"},{"key":"bibr4-09564624241248676","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2021.09.001"},{"key":"bibr5-09564624241248676","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2022.0008"},{"issue":"4","key":"bibr6-09564624241248676","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1007\/s10120-018-00909-5","volume":"22","author":"Bang Y-J","year":"2019","journal-title":"Gastric Cancer: Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association"},{"key":"bibr7-09564624241248676","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.59.5967"},{"key":"bibr8-09564624241248676","doi-asserted-by":"publisher","DOI":"10.1159\/000456714"},{"key":"bibr9-09564624241248676","unstructured":"Joint United Nations Program On HIV\/AIDS. 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