{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:48:13Z","timestamp":1787773693290,"version":"build-2784847793"},"reference-count":13,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T00:00:00Z","timestamp":1715731200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:p>In recent years, there has been an increase in Neisseria gonorrhoeae infections in Europe and Spain. Disseminated gonococcal infection is an uncommon clinical presentation that includes gonococcal arthritis. Improved antibiotic treatment has reduced the incidence of gonococcal arthritis. However, the increase in gonococcal infections may have increased the frequency of this clinical entity in recent times. We report five cases of gonococcal arthritis in patients in a tertiary-care hospital in the northern area of Madrid (Spain) from October 2022 to October 2023. Major cases occurred in male patients with unprotected sex and polyarticular symptoms requiring hospital admission and treatment with ceftriaxone and cefixime. The use of molecular techniques has allowed the detection of a greater number of culture-negative cases of gonococcal arthritis, as well as the detection of mutations associated with resistance to fluoroquinolone for switching to oral treatment.<\/jats:p>","DOI":"10.1177\/09564624241254877","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T13:42:57Z","timestamp":1715780577000},"page":"831-835","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Increase in gonococcal arthritis in Madrid, Spain, 2022-2023"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1856-1725","authenticated-orcid":false,"given":"Alfredo","family":"Maldonado-Barrueco","sequence":"first","affiliation":[{"name":"Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Sanz-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Rico-Nieto","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain"},{"name":"Infectious Diseases Unit, Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Grandioso-Vas","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain"},{"name":"CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Ruiz-Basti\u00e1n","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iker","family":"Falces-Romero","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain"},{"name":"CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juana","family":"Cacho-Calvo","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inmaculada","family":"Quiles-Melero","sequence":"additional","affiliation":[{"name":"Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,5,15]]},"reference":[{"key":"bibr1-09564624241254877","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkab037"},{"key":"bibr2-09564624241254877","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198506273122606"},{"key":"bibr3-09564624241254877","author":"National Center of Epidemiology","year":"2022","journal-title":"Epidemiologycal surveillance of sexually transmitted infections in Spain"},{"key":"bibr4-09564624241254877","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.rr7004a1"},{"key":"bibr5-09564624241254877","first-page":"1","volume":"63","author":"Papp JR","year":"2014","journal-title":"MMWR Recomm Rep"},{"key":"bibr6-09564624241254877","doi-asserted-by":"publisher","DOI":"10.1016\/S1521-6942(02)00125-0"},{"key":"bibr7-09564624241254877","doi-asserted-by":"publisher","DOI":"10.37201\/req\/058.2023"},{"key":"bibr8-09564624241254877","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-024-04786-y"},{"key":"bibr9-09564624241254877","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimce.2023.07.007"},{"key":"bibr10-09564624241254877","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000001794"},{"key":"bibr11-09564624241254877","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2013.07.011"},{"key":"bibr12-09564624241254877","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(22)00044-1"},{"key":"bibr13-09564624241254877","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-251050"}],"container-title":["International Journal of STD &amp; 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