{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:45:14Z","timestamp":1777927514869,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Kikuchi-Fujimoto lymphadenitis (or histiocytic necrotising lymphadenitis) is a rare disease that is usually benign and self-limiting. A higher prevalence is reported amongst East Asian populations. No clear etiology has been identified although it has been associated with some viruses, rarely the Human Immunodeficiency Virus (HIV) and autoimmune pathologies. To date, there has only been a handful of cases reported globally in association with HIV, and this association is even rarer in the Asian context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 20-year-old Asian ethnic Malay male, with no past medical history, presented with daily fevers and chills for 2\u00a0weeks associated with constitutional symptoms and bilateral non-tender cervical, axillary and inguinal lymphadenopathy. Full blood count showed lymphocytosis with large granular lymphocytes. HIV viral load returned positive at &gt;10\u00a0million copies\/mL. His absolute CD4 T helper cell count was 375\u00a0cells\/uL (7%). The rest of the infective and autoimmune workup were negative. Excision biopsy of an enlarged left cervical lymph node revealed Kikuchi lymphadenitis in the proliferative phase, with no evidence of lymphoproliferative disease. He was started on anti-retroviral therapy with resolution of the lymphadenopathy in 3\u00a0months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We present a case of Kikuchi lymphadenitis associated with HIV. This highlights that Kikuchi lymphadenitis may mimic sinister pathologies (such as tuberculosis and lymphoma) and that it needs to be considered in the differential diagnosis before empirical treatment for tuberculosis or invasive investigations for lymphoma are done.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624241282837","type":"journal-article","created":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T23:04:21Z","timestamp":1726268661000},"page":"1176-1179","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Kikuchi-Fujimoto lymphadenitis in a patient with human immunodeficiency virus infection: The importance of precision pathology"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9343-2069","authenticated-orcid":false,"given":"Wilson GW","family":"Goh","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, National University Hospital, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin MY","family":"Soo","sequence":"additional","affiliation":[{"name":"Fast and Chronic Programmes, Alexandra Hospital, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priscillia PS","family":"Lye","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, National University Hospital, Singapore, Singapore"},{"name":"Fast and Chronic Programmes, Alexandra Hospital, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Yong","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Pathology, National University Hospital, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul A","family":"Tambyah","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine, National University Hospital, Singapore, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,9,12]]},"reference":[{"key":"bibr1-09564624241282837","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-017-1521-y"},{"issue":"4","key":"bibr2-09564624241282837","first-page":"329","volume":"5","author":"Dorfman RF","year":"1988","journal-title":"Semin Diagn Pathol"},{"key":"bibr3-09564624241282837","doi-asserted-by":"publisher","DOI":"10.1002\/hon.2900080503"},{"key":"bibr4-09564624241282837","doi-asserted-by":"publisher","DOI":"10.1309\/1A6Y-YCKP-5AVF-QTYR"},{"issue":"2","key":"bibr5-09564624241282837","first-page":"149","volume":"20","author":"Mahajan T","year":"2007","journal-title":"SAVE Proc"},{"key":"bibr6-09564624241282837","first-page":"768321","volume":"2014","author":"Yogarajah M","year":"2014","journal-title":"Case Rep Rheumatol"},{"key":"bibr7-09564624241282837","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652002000500006"},{"key":"bibr8-09564624241282837","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(89)90033-0"},{"issue":"7","key":"bibr9-09564624241282837","first-page":"kex390.025","volume":"56","author":"Akhila K","year":"2017","journal-title":"Rheumatology"},{"key":"bibr10-09564624241282837","doi-asserted-by":"publisher","DOI":"10.1177\/0956462414545793"},{"key":"bibr11-09564624241282837","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199102000-00023"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241282837","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624241282837","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241282837","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:46:03Z","timestamp":1777675563000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624241282837"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,12]]},"references-count":11,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1177\/09564624241282837"],"URL":"https:\/\/doi.org\/10.1177\/09564624241282837","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,12]]}}}