{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:36:40Z","timestamp":1790660200848,"version":"4.1.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T00:00:00Z","timestamp":1727395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine the incidence of non-alcoholic fatty liver disease (NAFLD) by non-invasive methods in people living with HIV (PLWH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective cohort, in PLWH na\u00efve to antiretroviral therapy, starting bictegravir (BIC) or dolutegravir (DTG) at the Hospital de Infectolog\u00eda \u201cLa Raza\u201d, in Mexico City, from February 2021 to August 2023. We measured at baseline and 48\u00a0weeks triglycerides and glucose index (TyG), fatty liver index (FLI), hepatic steatosis index (HSI) and liver ultrasonography; relative risk (RR) for developing NAFLD was determined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At 48\u00a0weeks, TyG index in BIC-group 4.54 (IQR 4.36\u20134.75), in DTG-group 4.66 (IQR 4.49\u20134.80), p = .080; HSI in BIC-group 30.30 (IQR 28.12\u201333.70), in DTG-group 30.85 (IQR 28.02\u201334.50), p = .650; FLI in BIC-group 14.88 (IQR 7.91\u201331.80), in DTG-group 19.49 (IQR 8.49\u201332.28), p = .729; NAFLD was detected by US in 6 [10.3% (95%CI 4.8%\u201320.7%)] in BIC-group and, 7 [10.9% (95%CI 6.4%\u201320.9%)] in DTG-group, p = .916. Risk factors for NAFLD development were baseline BMI \u226525\u00a0kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , baseline HDL-c &lt;40\u00a0mg\/dL, and FIB-4 &gt;1.3 at 48\u00a0weeks.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There is a high incidence of NAFLD in PLWH who start a second generation INSTI at 48\u00a0weeks; baseline overweight, low HDL-cholesterol and FIB-4 &gt;1.3 at 48\u00a0weeks of treatment were independent risk factors for NAFLD development.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624241287886","type":"journal-article","created":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T14:38:43Z","timestamp":1727447923000},"page":"36-41","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Incidence of non-alcoholic fatty liver disease in antiretroviral therapy-na\u00efve people with human immunodeficiency virus who start DTG\/ABC\/3TC compared to BIC\/FTC\/TAF at 48-week follow-up"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9659-746X","authenticated-orcid":false,"given":"Ana Luz","family":"Cano D\u00edaz","sequence":"first","affiliation":[{"name":"Infectious Diseases Department, Hospital de Infectolog\u00eda \u201cLa Raza\u201d National Medical Center, Instituto Mexicano del Seguro Social, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salma","family":"Triana Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department, Hospital de Infectolog\u00eda \u201cLa Raza\u201d National Medical Center, Instituto Mexicano del Seguro Social, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria Elizabeth","family":"Salinas Vel\u00e1zquez","sequence":"additional","affiliation":[{"name":"Imagenology Department, Hospital de Infectolog\u00eda \u201cLa Raza\u201d National Medical Center, Instituto Mexicano del Seguro Social, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Antonio","family":"Mata Mar\u00edn","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department, Hospital de Infectolog\u00eda \u201cLa Raza\u201d National Medical Center, Instituto Mexicano del Seguro Social, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas Enrique","family":"Gayt\u00e1n Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Infectious Diseases Department, Hospital de Infectolog\u00eda \u201cLa Raza\u201d National Medical Center, Instituto Mexicano del Seguro Social, Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Mauss","sequence":"additional","affiliation":[{"name":"Center for HIV and Hepatogastroenterology, D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,9,27]]},"reference":[{"key":"bibr1-09564624241287886","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2022.0424"},{"key":"bibr2-09564624241287886","doi-asserted-by":"publisher","DOI":"10.1016\/j.lana.2021.100151"},{"key":"bibr3-09564624241287886","doi-asserted-by":"publisher","DOI":"10.21149\/11630"},{"key":"bibr4-09564624241287886","doi-asserted-by":"publisher","DOI":"10.1016\/j.rgmx.2018.11.007"},{"key":"bibr5-09564624241287886","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2016.08.117"},{"key":"bibr6-09564624241287886","doi-asserted-by":"publisher","DOI":"10.1177\/0956462416632428"},{"key":"bibr7-09564624241287886","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1904340"},{"key":"bibr8-09564624241287886","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1902824"},{"key":"bibr9-09564624241287886","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15320"},{"key":"bibr10-09564624241287886","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofac279"},{"key":"bibr11-09564624241287886","author":"World 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