{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:45:37Z","timestamp":1777927537446,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T00:00:00Z","timestamp":1734998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Human papillomavirus (HPV) infection profoundly affects women living with HIV (WLWH). This infection leads to cervical cancer (CC) and increased mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study monitored HPV infection in WLWH in Rio de Janeiro, Brazil, before (T1) and after (T2) 4\u00a0years of vaccination. HPV genotyping and the presence of intraepithelial lesions were investigated at both time points.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the 156 WLWH who received the quadrivalent HPV vaccine (4vHPV) at T1, 30 (19.2%) were initially found to have HPV DNA. After vaccination, only three (7%) of those who were HPV-negative at T1 tested positive for HPV. Most women who tested positive for HPV DNA at T1 had normal Pap smear results. However, this cohort also demonstrated a significant increase in cases of atypical squamous cells of uncertain significance and cervical intraepithelial neoplasia in PCR-negative HPV DNA samples at T2 (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .01). Conversely, women who initially tested negative for HPV DNA continued to exhibit normal Pap smear results in 2018 (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; .01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study highlights the persistence of HPV in WLWH despite vaccination and underscores the importance of continued molecular and cytologic screening. The findings enhance our understanding of vaccine effectiveness in this population and emphasize the need for tailored preventive strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624241310947","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T06:53:27Z","timestamp":1735023207000},"page":"304-308","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Persistence of HPV in cervical smears of vaccinated WLWH support for combined molecular testing and cytology screening"],"prefix":"10.1177","volume":"36","author":[{"given":"Milena Siqueira","family":"Pereira","sequence":"first","affiliation":[{"name":"Virological Diagnostic Laboratory, Department of Microbiology and Parasitology, Biomedical Institute, Universidade Federal Fluminense, Niteroi, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Maria Baeta","family":"Cavalcanti","sequence":"additional","affiliation":[{"name":"Virological Diagnostic Laboratory, Department of Microbiology and Parasitology, Biomedical Institute, Universidade Federal Fluminense, Niteroi, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charbell Miguel","family":"Haddad Kury","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Campos dos Goytacazes - Rio de Janeiro, Campos dos Goytacazes, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Willker Menezes","family":"da Rocha","sequence":"additional","affiliation":[{"name":"Virological Diagnostic Laboratory, Department of Microbiology and Parasitology, Biomedical Institute, Universidade Federal Fluminense, Niteroi, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1698-5989","authenticated-orcid":false,"given":"Rafael Brand\u00e3o","family":"Varella","sequence":"additional","affiliation":[{"name":"Virological Diagnostic Laboratory, Department of Microbiology and Parasitology, Biomedical Institute, Universidade Federal Fluminense, Niteroi, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,12,24]]},"reference":[{"key":"e_1_3_4_2_2","volume-title":"Global strategy to Accelerate the Elimination of cervical cancer as a Public health Problem","author":"World Health Organization","year":"2020","unstructured":"World Health Organization. Global strategy to Accelerate the Elimination of cervical cancer as a Public health Problem. Geneva: World Health Organization; 2020. Licence: CC BY-NC-SA 3.0 IGO. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789240014107 (Accessed 21 February 2024)."},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy1123"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djs395"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.805695"},{"key":"e_1_3_4_6_2","doi-asserted-by":"crossref","unstructured":"Bergman H Buckley BS Villanueva G et al. Comparison of different human papillomavirus (HPV) vaccines and the number of doses administered to prevent HPV-related disease in females and males. Cochrane Database Syst Rev. 2019; (11):CD013479.","DOI":"10.1002\/14651858.CD013479"},{"key":"e_1_3_4_7_2","volume-title":"Technical Note on the inclusion of victims of sexual violence as a priority group for vaccination against HPV","author":"Brazilian Ministry of Health. Health Surveillance Secretariat","year":"2023","unstructured":"Brazilian Ministry of Health. Health Surveillance Secretariat. Technical Note on the inclusion of victims of sexual violence as a priority group for vaccination against HPV. Brazil: Ministry of Health, 2023. Available from: https:\/\/www.gov.br\/saude\/pt-br\/assuntos\/noticias\/2023\/agosto\/arquivos\/nota-tecnica-63-2023-cgici-dpni-svsa-ms.pdf (Accessed 14 February 2024)."},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2020.1799666"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762012000100003"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2022.101585"},{"key":"e_1_3_4_11_2","volume-title":"WHO guideline for screening and treatment of cervical pre-cancer lesions for cervical cancer prevention","author":"World Health Organization","year":"2021","unstructured":"World Health Organization. WHO guideline for screening and treatment of cervical pre-cancer lesions for cervical cancer prevention, 2nd ed. Geneva: World Health Organization; 2021. Licence: CC BY-NC-SA 3.0 IGO. Available from: https:\/\/l1nq.com\/tyReu (Accessed 28 February 2024).","edition":"2"},{"issue":"2","key":"e_1_3_4_12_2","first-page":"135","article-title":"State of the art on HPV-related cervical lesions","volume":"36","author":"Golia D\u00b4AT","year":"2024","unstructured":"Golia D\u00b4AT, Cuccu I, Etrusco A, et al. State of the art on HPV-related cervical lesions. Gynaecology & Obstetrics 2024; 36(2): 135\u2013137.","journal-title":"Gynaecology & Obstetrics"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/03008916231208344"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2020.188476"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2010.08.007"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241310947","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624241310947","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624241310947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:46:20Z","timestamp":1777675580000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624241310947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,24]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1177\/09564624241310947"],"URL":"https:\/\/doi.org\/10.1177\/09564624241310947","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,24]]}}}