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We also examined whether sociodemographic factors moderated associations between APOE \u03b54 carrier status and MMSE scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A secondary analysis of cognitive, psychological, and sociodemographic data from the Miami Adult Studies on HIV (MASH) cohort (\n                      <jats:italic>n<\/jats:italic>\n                      = 493) was completed. Banked blood samples underwent APOE genotyping. Bivariate analyses examined potential differences across participants by HIV and\/or HCV statuses and by APOE \u03b54 carrier status. Multiple linear regression was conducted to test the adjusted moderation effect of each sociodemographic variable between APOE \u03b54 carrier status and MMSE scores within each group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sociodemographic factors, such as income, education, food insecurity, and employment influenced associations between APOE \u03b54 carrier status and MMSE scores among participants with HIV\/HCV. Participants with APOE \u03b54 genotypes living with HCV had higher MMSE scores than non-APOE \u03b54 carriers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These results reinforce the need for future studies examining (1) the impact of APOE genotype on cognitive functioning while considering socioeconomic factors and (2) the influence of socioeconomic factors on cognitive scores among individuals living with HIV and or HCV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624251324968","type":"journal-article","created":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T06:37:17Z","timestamp":1748500637000},"page":"719-730","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The influence of socioeconomic factors and apolipoprotein \u03b5 genotype on cognitive outcomes in a 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