{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T16:00:50Z","timestamp":1782316850626,"version":"3.54.5"},"reference-count":11,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2025,12]]},"abstract":"\n Urethritis is a frequent lower urinary tract infection often linked to sexually transmitted infections (STIs). While\n Neisseria gonorrhoeae<\/jats:italic>\n and\n Chlamydia trachomatis<\/jats:italic>\n are the main pathogens, other microorganisms such as\n Mycoplasma genitalium<\/jats:italic>\n ,\n Trichomonas vaginalis<\/jats:italic>\n , and\n Ureaplasma urealyticum<\/jats:italic>\n may also be involved. In over half of non-gonococcal urethritis (NGU) cases, no causative agent is identified. We present the case of a 37-year-old man with scrotal pain, painful ejaculation, dysuria, and urethral discharge following a single unprotected sexual encounter. Initial STI PCR was positive for\n Ureaplasma urealyticum<\/jats:italic>\n , and azithromycin was prescribed. Symptoms persisted, and a urethral culture revealed\n Streptococcus urinalis<\/jats:italic>\n , confirmed by MALDI-TOF MS and 16S rRNA sequencing. Gram staining showed numerous leukocytes and Gram-positive cocci in chains. A second urethral swab yielded the same organism. The isolate was fully susceptible to all tested antibiotics. Although\n S. urinalis<\/jats:italic>\n has been described in urinary tract infections and sepsis, to our knowledge, this is the first reported case suggesting a possible role in male urethritis. While prostatitis or epididymitis cannot be ruled out, the repeated isolation of\n S. urinalis<\/jats:italic>\n and persistent symptoms support its potential pathogenicity. This case adds to growing evidence implicating\n S. urinalis<\/jats:italic>\n in genitourinary tract infections.\n <\/jats:p>","DOI":"10.1177\/09564624251365133","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T10:01:53Z","timestamp":1754474513000},"page":"1057-1059","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Streptococcus urinalis:<\/i>\n A potential case of male urethritis caused by a novel pathogen"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4039-2638","authenticated-orcid":false,"given":"Jorge","family":"Ligero-L\u00f3pez","sequence":"first","affiliation":[{"name":"Hospital Cl\u00ednico Universitario Lozano Blesa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Beltr\u00e1n-Rosel","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario Lozano Blesa"},{"name":"Institute of Environmental Sciences (IUCA)"},{"name":"Universidad de Zaragoza"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Duc\u00f3ns-M\u00e1rquez","sequence":"additional","affiliation":[{"name":"Hospital de Alca\u00f1iz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Escribano-Pardo","sequence":"additional","affiliation":[{"name":"Oliver Health Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Luis","family":"Juan-Ba\u00f1\u00f3n","sequence":"additional","affiliation":[{"name":"Valentian Institute of Microbiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"L\u00f3pez-Alonso","sequence":"additional","affiliation":[{"name":"\u00c9pila Health Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,8,6]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-44733-z"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ755"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.02213-22"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00006-11"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00952-06"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir517"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2017.03.017"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/sti.78.6.445"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2015-052214"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-50-3-1173"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.039792-0"}],"container-title":["International Journal of STD & AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624251365133","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624251365133","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624251365133","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:46:57Z","timestamp":1777675617000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624251365133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,6]]},"references-count":11,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1177\/09564624251365133"],"URL":"https:\/\/doi.org\/10.1177\/09564624251365133","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,6]]}}}