{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:45:35Z","timestamp":1777927535058,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:00:00Z","timestamp":1755216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100006661","name":"United Nations Population Fund","doi-asserted-by":"publisher","award":["MEX07SRH"],"award-info":[{"award-number":["MEX07SRH"]}],"id":[{"id":"10.13039\/100006661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background\/Objectives<\/jats:title>\n                    <jats:p>Transgender women in Mexico face a high HIV prevalence, yet they remain insufficiently engaged in pre-exposure prophylaxis (PrEP). This study aimed to evaluate willingness to use HIV pre-exposure prophylaxis (PrEP) and its connection to risk behaviors among transgender women in Mexico.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In 2021, a cross-sectional study was conducted among Mexican transgender women to assess HIV risk factors and willingness to use PrEP. We used Latent Class Analysis to cluster participants with similar HIV risk behaviors, and multivariable logistic regression to identify covariates of willingness to use PrEP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 266 transgender women, 40% were aware of PrEP, yet 78% reported willingness to use it after a brief introduction. Only 25% of the participants perceived themselves at high HIV risk. Through Latent Class Analysis, three classes were identified: 1) transactional sex with lower risk (10%); 2) no transactional sex with higher risk (25%); and 3) transactional sex with higher risk (65%), with reported willingness to use PrEP at 61%, 66% and 85%, respectively. In the multivariable model, belonging to class 3 (vs class 1) was associated with higher willingness to use PrEP (aOR:3.3; CI:1.2\u20139.5).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Willingness to use PrEP aligned with HIV risk in those with a higher risk (class 3) and lower risk (class 1), but not in those at higher risk despite not reporting transactional sex (class 2). Therefore, not all who could benefit from PrEP may want it. Strategies are needed to promote PrEP\u2019s awareness and willingness to use considering the needs of transgender women subgroups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624251367489","type":"journal-article","created":{"date-parts":[[2025,8,16]],"date-time":"2025-08-16T01:38:01Z","timestamp":1755308281000},"page":"1028-1037","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Willingness to use pre-exposure prophylaxis among Mexican transgender women: A latent class analysis"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1274-8537","authenticated-orcid":false,"given":"Heleen","family":"Vermandere","sequence":"first","affiliation":[{"name":"National Institute of Public Health of Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7354-1698","authenticated-orcid":false,"given":"Santiago","family":"Aguilera-Mijares","sequence":"additional","affiliation":[{"name":"National Institute of Public Health of Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaqu\u00edn","family":"Escobar Trinidad","sequence":"additional","affiliation":[{"name":"National Institute of Public Health of Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Cerecero-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Imperial College"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Bautista-Arredondo","sequence":"additional","affiliation":[{"name":"National Institute of Public Health of Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,8,15]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0260063"},{"key":"e_1_3_7_3_2","unstructured":"WHO. Differentiated and simplified pre-exposure prophylaxis for HIV prevention. https:\/\/apps.who.int\/bookorders 2022."},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001105"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/trgh.2019.0076"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-03050-6"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1521\/aeap.2020.32.3.212"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/trgh.2020.0003"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(20)30119-3"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001839"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-019-02501-z"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1089\/trgh.2016.0033"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/09564624231152781"},{"key":"e_1_3_7_14_2","volume-title":"Informe Hist\u00f3rico de VIH 1er Trimestre de 2024","author":"Direcci\u00f3n de Vigilancia Epidemiol\u00f3gica de Enfermedades Transmisibles","year":"2024","unstructured":"Direcci\u00f3n de Vigilancia Epidemiol\u00f3gica de Enfermedades Transmisibles. Sistema de Vigilancia Epidemiol\u00f3gica de VIH. Informe Hist\u00f3rico de VIH 1er Trimestre de 2024. https:\/\/www.gob.mx\/cms\/uploads\/attachment\/file\/917597\/VIH_DVEET_1erTrim_2024.pdf, 2024 (Accessed 18 June 2024)."},{"key":"e_1_3_7_15_2","unstructured":"Secretar\u00eda de Salud. Informe Nacional Del Monitoreo de Compromisos y Objetivos Ampliados Para Poner Fin al Sida (Informe GAM). https:\/\/www.gob.mx\/censida\/documentos\/informe-nacional-del-monitoreo-de-compromisos-y-objetivos-ampliados-para-poner-fin-al-sida-informe-gam-mexico-2018?idiom=es (2018 Accessed 20 March 2023)."},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-017-1931-2"},{"key":"e_1_3_7_17_2","doi-asserted-by":"publisher","DOI":"10.21149\/spm.v57s2.7596"},{"key":"e_1_3_7_18_2","unstructured":"Centro Nacional para la Prevenci\u00f3n y Control del VIH y el Sida. 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