{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:46:29Z","timestamp":1777927589482,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T00:00:00Z","timestamp":1755820800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T00:00:00Z","timestamp":1755820800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"University College London in partnership with the UK Health Security Agency"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>HIV-PrEP is a key component of HIV combination prevention and has been routinely available through oral formulations (i.e. oral tablets) across sexual health services (SHSs) in the UK since 2020. We used data from a large, online community survey to assess the acceptability and preference of different HIV-PrEP modalities among gay, bisexual, and other men who have sex with men (GBMSM) and gender-diverse individuals living in the UK.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using data collected from the \u2018Reducing inequalities in Sexual Health\u2019 (RiiSH) survey, an online community survey of 1106 GBMSM and gender-diverse individuals having sex with men (November\/December 2023), we performed a secondary analysis examining HIV-PrEP modality acceptability and preference (e.g. oral, long acting injectable, gel, or patch) (%) by HIV-PrEP history (never, in lookback period of last 3\u20134\u00a0months since survey completion). Where \u22652 modalities were indicated, participants were asked to specify a single preferred modality. Single choice options were assumed to be the preferred HIV-PrEP modality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Irrespective of HIV-PrEP history, long acting injectables were highly acceptable (&gt;70%) and the preferred modality (58% [222\/386] by those never having used HIV-PrEP, 73% [75\/103] in those without HIV-PrEP use in the lookback, 74% [314\/424] in those with HIV-PrEP use in the lookback).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We found high acceptability of the use of injectables, with general preference over oral tablets. If injectable HIV-PrEP becomes available at SHSs in England, these modalities could have positive impacts on HIV-PrEP delivery, use, and access.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624251369093","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T07:33:00Z","timestamp":1755847980000},"page":"30-35","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Thinking beyond the tablet: Acceptability of different HIV-PrEP modalities among GBMSM and gender-diverse individuals having sex with men in the UK"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1900-8892","authenticated-orcid":false,"given":"Dana","family":"Ogaz","sequence":"first","affiliation":[{"name":"UK Health Security Agency"},{"name":"The National Institute for Health and Care Research Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in Partnership with the UK Health Security Agency"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"Ratna","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8963-4676","authenticated-orcid":false,"given":"Hridhya","family":"Vijayan","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2049-9040","authenticated-orcid":false,"given":"Stephanie J","family":"Migchelsen","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Reid","sequence":"additional","affiliation":[{"name":"The National Institute for Health and Care Research Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in Partnership with the UK Health Security Agency"},{"name":"University College London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1741-1449","authenticated-orcid":false,"given":"Dolores","family":"Mullen","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn","family":"Phillips","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleanor","family":"Bell","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Djuretic","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Will","family":"Nutland","sequence":"additional","affiliation":[{"name":"The Love Tank"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine H","family":"Mercer","sequence":"additional","affiliation":[{"name":"The National Institute for Health and Care Research Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in Partnership with the UK Health Security Agency"},{"name":"University College London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Folkard","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3020-9916","authenticated-orcid":false,"given":"John","family":"Saunders","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"},{"name":"The National Institute for Health and Care Research Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in Partnership with the UK Health Security Agency"},{"name":"University College London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2060-7286","authenticated-orcid":false,"given":"Hamish","family":"Mohammed","sequence":"additional","affiliation":[{"name":"UK Health Security Agency"},{"name":"The National Institute for Health and Care Research Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in Partnership with the UK Health Security Agency"},{"name":"University College London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,8,22]]},"reference":[{"key":"e_1_3_7_2_2","volume-title":"HIV testing, PrEP, new HIV diagnoses and care outcomes for people accessing HIV services: 2024 report. The annual official statistics data release (data to end of December 2023)","author":"Kitt HSA","year":"2024","unstructured":"Kitt HSA, Chau C, Okumu-Camerra K, et al. HIV testing, PrEP, new HIV diagnoses and care outcomes for people accessing HIV services: 2024 report. The annual official statistics data release (data to end of December 2023), 2024. https:\/\/www.gov.uk\/government\/statistics\/hiv-annual-data-tables\/hiv-testing-prep-new-hiv-diagnoses-and-care-outcomes-for-people-accessing-hiv-services-2024-report (accessed 16 December 2024)."},{"key":"e_1_3_7_3_2","volume-title":"Sexual orientation and gender identity quality information for census 2021","author":"Office for National Statistics","year":"2024","unstructured":"Office for National Statistics. Sexual orientation and gender identity quality information for census 2021, 2024. https:\/\/www.ons.gov.uk\/peoplepopulationandcommunity\/culturalidentity\/sexuality\/methodologies\/sexualorientationandgenderidentityqualityinformationforcensus2021 (accessed 03 March 2025)."},{"key":"e_1_3_7_4_2","volume-title":"British HIV association\/British association for sexual health and HIV\/British infection association adult HIV testing guidelines 2020","author":"British HIV Association, British Association for Sexual Health and HIV and British Infection Association","year":"2020","unstructured":"British HIV Association, British Association for Sexual Health and HIV and British Infection Association. British HIV association\/British association for sexual health and HIV\/British infection association adult HIV testing guidelines 2020, 2020. https:\/\/www.bhiva.org\/file\/5f68c0dd7aefb\/HIV-testing-guidelines-2020.pdf (accessed 1 10 2020)."},{"key":"e_1_3_7_5_2","doi-asserted-by":"crossref","first-page":"s2","DOI":"10.1111\/hiv.12426","article-title":"British HIV association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2015","volume":"17","author":"Churchill D","year":"2016","unstructured":"Churchill D, Waters L, Ahmed N, et al. British HIV association guidelines for the treatment of HIV-1-positive adults with antiretroviral therapy 2015. HIV Med 2016; 17 Suppl 4: s2\u2013s104.","journal-title":"HIV Med"},{"key":"e_1_3_7_6_2","doi-asserted-by":"crossref","first-page":"s2","DOI":"10.1111\/hiv.12718","article-title":"BHIVA\/BASHH guidelines on the use of HIV pre-exposure prophylaxis (PrEP) 2018","volume":"20","author":"Brady M","year":"2019","unstructured":"Brady M, Rodger A, Asboe D, et al. BHIVA\/BASHH guidelines on the use of HIV pre-exposure prophylaxis (PrEP) 2018. HIV Med 2019; 20 Suppl 2: s2\u2013s80.","journal-title":"HIV Med"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(23)00261-8"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2101016"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2411858"},{"key":"e_1_3_7_10_2","volume-title":"Cabotegravir for preventing HIV-1 in adults and young people [ID6255]: in development [GID-TA11304]","author":"National Institute for Health and Care Excellence","year":"2024","unstructured":"National Institute for Health and Care Excellence. Cabotegravir for preventing HIV-1 in adults and young people [ID6255]: in development [GID-TA11304], 2024. https:\/\/www.nice.org.uk\/guidance\/indevelopment\/gid-ta11304 (accessed 24 March 2025)."},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.2196\/publichealth.9010"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2021-055039"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2014.19.48.20981"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.2196\/62801"},{"key":"e_1_3_7_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/20499361231153548"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(18)30215-7"},{"key":"e_1_3_7_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-021-03344-3"},{"key":"e_1_3_7_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-016-3149-z"},{"key":"e_1_3_7_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2015-052389"},{"key":"e_1_3_7_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-020-01295-0"},{"key":"e_1_3_7_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2023-055989"},{"key":"e_1_3_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(23)00256-4"},{"key":"e_1_3_7_23_2","doi-asserted-by":"publisher","DOI":"10.1177\/09564624241273778"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624251369093","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624251369093","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624251369093","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:46:59Z","timestamp":1777675619000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624251369093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,22]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1177\/09564624251369093"],"URL":"https:\/\/doi.org\/10.1177\/09564624251369093","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,22]]}}}