{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:46:24Z","timestamp":1777927584476,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:00:00Z","timestamp":1759449600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"publisher","award":["13990, 18812, 23485"],"award-info":[{"award-number":["13990, 18812, 23485"]}],"id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pre-exposure prophylaxis (PrEP) for Human Immunodeficiency Virus (HIV) is safe and effective, but its implementation is suboptimal with the US South having disproportionately high numbers of new HIV infections and low PrEP use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Parkland Health in Dallas, Texas has implemented interventions to improve PrEP uptake. A retrospective review was conducted of targeted PrEP offers in 2022 to eligible patients aged &gt;=16 years to compare differences between those who accepted versus declined PrEP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 2,219 patients offered PrEP, 287 were excluded. Of the remaining 1,932, 195 (10%) accepted a PrEP offer. Those who accepted were more likely to be from a younger age group (16\u201325 vs &gt; 55\u00a0years,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      -value &lt;0.01), men who have sex with men (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      -value &lt;0.01), and transgender females with male partners (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      -value &lt;0.01). Other positive predictors of PrEP acceptance included being insured (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      -value 0.01), sero-discordant partner (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      -value &lt;0.01), and pregnancy (p-value &lt;0.01). Patients who accepted were more likely to have received multiple interventions (145\/195 (74.36%) vs 580\/1737 (33.39%),\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      -value &lt;0.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A multipronged approach to increasing PrEP uptake in a health system in the South reached a variety of eligible patients. Future efforts should focus on improving PrEP engagement for Black, uninsured, heterosexual, and older individuals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624251382273","type":"journal-article","created":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T20:20:42Z","timestamp":1759522842000},"page":"222-227","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Population characteristics in patients accepting versus declining HIV pre-exposure prophylaxis after targeted offer in large public hospital in the US south"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5626-5900","authenticated-orcid":false,"given":"Abbye W.","family":"Frederick","sequence":"first","affiliation":[{"name":"University of Texas Southwestern Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3196-6118","authenticated-orcid":false,"given":"Kristin S.","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Parkland Health"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ank E.","family":"Nijhawan","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virali","family":"Soni","sequence":"additional","affiliation":[{"name":"Parkland Health"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9364-4053","authenticated-orcid":false,"given":"Song","family":"Zhang","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily H.","family":"Adhikari","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Turknett","sequence":"additional","affiliation":[{"name":"Parkland Health"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"King","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,3]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.2591"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001145"},{"key":"e_1_3_8_4_2","unstructured":"Office of Infectious Disease and HIV\/AIDS Policy. Key EHE strategies. https:\/\/www.hiv.gov\/federal-response\/ending-the-hiv-epidemic\/key-strategies (2022 accessed 16 January 2023)."},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-019-00447-4"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-016-1663-8"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw701"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofae056"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000003464"},{"key":"e_1_3_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(19)30137-7"},{"key":"e_1_3_8_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(19)30139-0"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac775"},{"key":"e_1_3_8_13_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-2524-4993"},{"key":"e_1_3_8_14_2","unstructured":"Parkland Health & Hospital System | Dallas County Health and Human Services. Dallas County community health needs assessment 2019. https:\/\/www.parklandhealth.org\/Uploads\/Public\/Documents\/PDFs\/Health-Dashboard\/CHNA_2019.pdf (2019 accessed 6 May 2024)."},{"key":"e_1_3_8_15_2","unstructured":"Centers for Disease Control and Prevention. Fast facts: HIV in the US by race and ethnicity. https:\/\/www.cdc.gov\/hiv\/data-research\/facts-stats\/race-ethnicity.html (2024 accessed 2 May 2025)."},{"key":"e_1_3_8_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001165"},{"key":"e_1_3_8_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2313708"},{"key":"e_1_3_8_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-024-00697-x"},{"key":"e_1_3_8_19_2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2025.0058"},{"key":"e_1_3_8_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004709"},{"key":"e_1_3_8_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000002971"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624251382273","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624251382273","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624251382273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:47:09Z","timestamp":1777675629000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624251382273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,3]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1177\/09564624251382273"],"URL":"https:\/\/doi.org\/10.1177\/09564624251382273","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,3]]}}}