{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T14:01:19Z","timestamp":1787320879936,"version":"build-2736575974"},"reference-count":34,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:00:00Z","timestamp":1767916800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Ministry of Health of the Autonomous City of Buenos Aires","award":["Resolution N\u00b0 1549-MSGC-2022"],"award-info":[{"award-number":["Resolution N\u00b0 1549-MSGC-2022"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transgender women (TGW) face a disproportionately high HIV burden, yet real-world evidence on their engagement in the care cascade is scarce. This study analysed HIV care cascade outcomes and associated factors in a large Argentinian cohort to identify key challenges and inform public health strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective cohort study of TGW with confirmed HIV linked to care at a public hospital in Buenos Aires (2011\u20132022). We analyzed 12-month retention in care, antiretroviral therapy (ART) use, and virologic suppression using bivariate and multivariate logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 240 TGW included, 186 completed 12-months follow-up. The cascade outcomes were: 71.5% retained in care; 87.9% on ART among those retained; and 70.7% virologically suppressed among those on ART. In multivariate analysis, ART initiation at linkage was the strongest predictor of retention (aOR: 35.93; 95%CI: 9.72\u2013132.75), while baseline cocaine use was associated with a lower likelihood of being on ART (aOR: 0.17; 95%CI: 0.04\u20130.68).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Significant gaps persist in the HIV care cascade for TGW in this real-world setting. While immediate ART initiation is a powerful tool for retention, structural barriers like substance use require integrated interventions. This evidence is critical for designing effective public health strategies to improve health equity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09564624251411091","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:30:17Z","timestamp":1767983417000},"page":"640-647","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Bridging gaps in HIV care for transgender women: A decade of real-world evidence"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9038-0785","authenticated-orcid":false,"given":"Mauro","family":"Bertolini","sequence":"first","affiliation":[{"name":"Infectious Diseases Division, Hospital General de Agudos Dr. Juan A. Fern\u00e1ndez, Autonomous City of Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2210-5965","authenticated-orcid":false,"given":"Jos\u00e9 \u00c1. E.","family":"Barletta","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Hospital General de Agudos Dr. Juan A. Fern\u00e1ndez, Autonomous City of Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia E.","family":"Frola","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Hospital General de Agudos Dr. Juan A. Fern\u00e1ndez, Autonomous City of Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Rol\u00f3n","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Hospital General de Agudos Dr. Juan A. Fern\u00e1ndez, Autonomous City of Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Pan American Health Organization. Framework for monitoring HIV\/STI services for key populations in Latin America and the Caribbean. 2019. https:\/\/www.paho.org\/es\/documentos\/marco-monitoreo-servicios-relacionados-con-vih-its-para-grupos-poblacion-clave-america"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(12)70315-8"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2011.05.007"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-011-0053-5"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12914-019-0187-5"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2011.300433"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0000000000000030"},{"key":"e_1_3_3_9_2","unstructured":"Lambda Legal. When health care isn\u2019t caring. 2025. https:\/\/legacy.lambdalegal.org\/publications\/when-health-care-isnt-caring"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1255"},{"issue":"98","key":"e_1_3_3_11_2","first-page":"1","article-title":"Factores contextuales, sociales e individuales como barreras y facilitadores para el acceso a la salud de mujeres trans: desde la perspectiva de la comunidad","volume":"26","author":"Zalazar V","year":"2018","unstructured":"Zalazar V, Ar\u00edstegui I, Cardozo N, et al. Factores contextuales, sociales e individuales como barreras y facilitadores para el acceso a la salud de mujeres trans: desde la perspectiva de la comunidad. Actualizaciones en Sida e Infectolog\u00eda 2018; 26(98): 1\u201314.","journal-title":"Actualizaciones en Sida e Infectolog\u00eda"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12939-014-0081-7"},{"key":"e_1_3_3_13_2","volume-title":"HIV strategic information for impact: cascade data use manual: to identify gaps in HIV and health services for programme improvement: user manual","author":"World Health Organization","year":"2018","unstructured":"World Health Organization. HIV strategic information for impact: cascade data use manual: to identify gaps in HIV and health services for programme improvement: user manual. WHO, 2018. https:\/\/www.who.int\/publications\/i\/item\/cascade-data-use-manual-to-identify-gaps-in-hiv-and-health-services-for-programme-improvement"},{"issue":"6","key":"e_1_3_3_14_2","first-page":"448","article-title":"The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital","volume":"40","author":"Cesar C","year":"2016","unstructured":"Cesar C, Blugerman G, Valiente JA, et al. The HIV care cascade in Buenos Aires, Argentina: results in a tertiary referral hospital. Rev Panam Salud P\u00fablic 2016; 40(6): 448\u2013454.","journal-title":"Rev Panam Salud P\u00fablic"},{"key":"e_1_3_3_15_2","unstructured":"Gobierno de la Ciudad de Buenos Aires. Epidemiolog\u00eda y gesti\u00f3n del VIH y otras ITS. https:\/\/buenosaires.gob.ar\/epidemiologia-y-gestion\/epidemiologia-y-gestion-del-vih-y-otras-its"},{"key":"e_1_3_3_16_2","volume-title":"Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach: 2010 revision","author":"World Health Organization","year":"2010","unstructured":"World Health Organization. Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach: 2010 revision. WHO, 2010. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK138540\/"},{"key":"e_1_3_3_17_2","volume-title":"Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach","author":"World Health Organization","year":"2013","unstructured":"World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach. WHO, 2013. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK195400\/"},{"key":"e_1_3_3_18_2","volume-title":"Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV","author":"World Health Organization","year":"2015","unstructured":"World Health Organization. Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV. WHO, 2015. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK327115\/"},{"key":"e_1_3_3_19_2","volume-title":"Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection","author":"World Health Organization","year":"2016","unstructured":"World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. 2nd ed. WHO, 2016. ANNEX 10. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK374293\/","edition":"2"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0279996"},{"key":"e_1_3_3_21_2","volume-title":"WHO recommends dolutegravir as preferred HIV treatment option in all populations","author":"World Health Organization","year":"2019","unstructured":"World Health Organization. WHO recommends dolutegravir as preferred HIV treatment option in all populations. 2019. https:\/\/www.who.int\/news\/item\/22-07-2019-who-recommends-dolutegravir-as-preferred-hiv-treatment-option-in-all-populations"},{"issue":"32","key":"e_1_3_3_22_2","article-title":"Ley de Identidad de G\u00e9nero","author":"Argentina","year":"2012","unstructured":"Argentina. Ley de Identidad de G\u00e9nero. Bolet\u00edn Oficial de la Rep\u00fablica Argentina 2012; CXX(32,404). https:\/\/www.argentina.gob.ar\/normativa\/nacional\/ley-26743-197860","journal-title":"Bolet\u00edn Oficial de la Rep\u00fablica Argentina"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1080\/15532739.2017.1314796"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(25)00004-9"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25270"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2019.0013"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0268226"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2023.46.20.40772"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1506816"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgph.0000259"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.11606\/s1518-8787.2023057004219"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-016-1398-6"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1023\/B:JOHE.0000016716.99847.9b"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1080\/08897077.2019.1706695"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001087"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624251411091","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09564624251411091","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09564624251411091","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:47:29Z","timestamp":1777675649000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09564624251411091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,9]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1177\/09564624251411091"],"URL":"https:\/\/doi.org\/10.1177\/09564624251411091","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,9]]}}}