{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:47:18Z","timestamp":1777927638762,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1990,9,1]],"date-time":"1990-09-01T00:00:00Z","timestamp":652147200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[1990,9]]},"abstract":"<jats:p>Neisseria gonorrhoeae culture gave a positive result in 42 of 64 male adults with purulent urethral discharge. The majority of the infections were acquired outside Libya Twenty-seven strains (64.3%) were non-penicillinase producing (NPPNG) and 15 (35.7%) were penicillinase producing (PPNG) by starch paper technique. Antimicrobial susceptibility of the strains to 5 antibiotics was carried out by agar-plate dilution technique. Twenty-three NPPNG strains (54.8%) were susceptible to penicillin with a minimum inhibitory concentration (MIC) of \u22640.5 \u03bcg\/ml. In 4 strains (9.5%), a high resistance to penicillin (MIC \u226516 \u03bcg\/ml) appeared to be chromosomally-mediated (CMRNG). All PPNG strains were resistant to penicillin (MIC \u22651 \u03bcg\/ml). While resistance to erythromycin (MIC \u2265 1 \u03bcg\/ml) and tetracycline (MIC \u2265 1 \u03bcg\/ml) was observed in 5 strains, resistance to kanamycin (MIC 32 \u03bcg\/ml) and spectinomycin (MIC 64 \u03bcg\/ml) was present in only one strain. Whereas no significant differences were recorded in MICs of erythromycin, tetracycline, kanamycin and spectinomycin between NPPNG and PPNG strains, one PPNG strain was found to be resistant in vitro to all 5 antibiotics.<\/jats:p>","DOI":"10.1177\/095646249000100508","type":"journal-article","created":{"date-parts":[[2017,1,16]],"date-time":"2017-01-16T19:38:39Z","timestamp":1484595519000},"page":"343-345","source":"Crossref","is-referenced-by-count":2,"title":["Antimicrobial Susceptibility of Non-Penicillinase and Penicillinase-Producing\n                    <i>Neisseria Gonorrhoeae<\/i>\n                    Strains Isolated in Tripoli, Libya"],"prefix":"10.1177","volume":"1","author":[{"given":"M T","family":"Elghoul","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology and Immunology, Faculty of Medicine, The Great Al-Fateh University of Medical Science, Tripoli, Libya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R M","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Immunology, Faculty of Medicine, The Great Al-Fateh University of Medical Science, Tripoli, Libya"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1990,9,1]]},"reference":[{"key":"bibr1-095646249000100508","unstructured":"Park JE, Zaheer M, Aly HK. A short textbook on community medicine, 1st edn. Tripoli: Al-Fateh University Press, 1982:156."},{"key":"bibr2-095646249000100508","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.285.6338.337"},{"key":"bibr3-095646249000100508","first-page":"37","volume":"16","author":"Guttierrez GT.","year":"1980","journal-title":"Mod Med Asia"},{"key":"bibr4-095646249000100508","first-page":"232","volume":"59","author":"Ng WS","year":"1983","journal-title":"Br J Vener Dis"},{"key":"bibr5-095646249000100508","first-page":"221","volume":"2","author":"Joshi RM","year":"1985","journal-title":"Eur J Sex Transm Dis"},{"key":"bibr6-095646249000100508","first-page":"257","volume":"40","author":"Reyn A.","year":"1969","journal-title":"Bull WHO"},{"key":"bibr7-095646249000100508","first-page":"217","volume":"46","author":"Willcox RR.","year":"1970","journal-title":"Br J Vener Dis"},{"key":"bibr8-095646249000100508","volume-title":"WHO Expert Committee on Venereal Diseases and Treponematoses","year":"1986"},{"key":"bibr9-095646249000100508","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6085.500"},{"key":"bibr10-095646249000100508","first-page":"408","volume":"33","author":"Centers for Disease Control","year":"1984","journal-title":"MMWR"},{"key":"bibr11-095646249000100508","first-page":"62","volume-title":"Immunobiology of Neisseria gonorrhoeae","author":"Thornsberry C","year":"1978"},{"key":"bibr12-095646249000100508","first-page":"74","volume":"37","author":"Joshi RM","year":"1985","journal-title":"Trap Geogr Med"},{"key":"bibr13-095646249000100508","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-198907000-00003"},{"key":"bibr14-095646249000100508","first-page":"54","volume":"49","author":"Reyn A","year":"1973","journal-title":"Br J Vener Dis"},{"key":"bibr15-095646249000100508","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198707303170504"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/095646249000100508","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/095646249000100508","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:48:18Z","timestamp":1777675698000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/095646249000100508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,9]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1990,9]]}},"alternative-id":["10.1177\/095646249000100508"],"URL":"https:\/\/doi.org\/10.1177\/095646249000100508","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,9]]}}}