{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:48:36Z","timestamp":1777927716705,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[1994,11,1]],"date-time":"1994-11-01T00:00:00Z","timestamp":783648000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J STD AIDS"],"published-print":{"date-parts":[[1994,11]]},"abstract":"<jats:p>\n                    The cumulative incidence of sexually transmitted diseases (STD) in a cohort of 51 (35 female, 16 male) HIV-1 seropositive STD clinic attenders who had acquired HIV-1 infection via heterosexual transmission was investigated through a retrospective review of the case notes. The women were followed up for a mean 11.6 months and the men for 18 months. Thirty-one (88%) of the women and 13 (81%) of the men were of sub-Saharan African origin. Approximately half of the subjects were first diagnosed as HIV-1 positive with CD4 counts &lt;200\u00d710\n                    <jats:sup>6<\/jats:sup>\n                    \/1 and a quarter with CD4 counts &lt;50\u00d710\n                    <jats:sup>6<\/jats:sup>\n                    \/1. STDs detected in women were: genital herpes 15 (43%), Candida 12 (34%), bacterial vaginosis 9 (25%), and in men: genital herpes 6 (38%), non-gonococcal urethritis 4 (25%). No cases of gonorrhoea were detected. At the time of first diagnosis of genital herpes at the clinic, the mean CD4 count in women was 275\u00d710\n                    <jats:sup>6<\/jats:sup>\n                    \/1 and in men 285\u00d710\n                    <jats:sup>6<\/jats:sup>\n                    \/1. Genital herpes was the AIDS defining diagnosis in 3 of the women.\n                  <\/jats:p>\n                  <jats:p>The recognized risk of HIV transmission via genital lesions should be stressed in HIV-1 positive subjects with genital herpes. The incidence of other STD was low\u2014both knowledge of HIV status and safer sex counselling may limit unsafe sexual behaviour and should be evaluated further as a strategy for limiting the spread of HIV-1 infection.<\/jats:p>","DOI":"10.1177\/095646249400500607","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T14:57:17Z","timestamp":1484146637000},"page":"415-418","source":"Crossref","is-referenced-by-count":19,"title":["High Cumulative Incidence of Genital Herpes Amongst HIV-1 Seropositive Heterosexuals in South London"],"prefix":"10.1177","volume":"5","author":[{"given":"Nigel","family":"O'Farrell","sequence":"first","affiliation":[{"name":"Lloyd Clinic, Guy's Hospital, London SE1, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart J","family":"Tovey","sequence":"additional","affiliation":[{"name":"Lloyd Clinic, Guy's Hospital, London SE1, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1994,11,1]]},"reference":[{"key":"bibr1-095646249400500607","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-199219020-00001"},{"key":"bibr2-095646249400500607","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/163.2.233"},{"key":"bibr3-095646249400500607","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199301000-00015"},{"key":"bibr4-095646249400500607","first-page":"S1","volume":"3","author":"Report of a Working Group","year":"1993","journal-title":"Commun Dis Rep"},{"key":"bibr5-095646249400500607","volume-title":"Prevention of sexual transmission of Human Immunodeficiency virus","author":"World Health Organization","year":"1990"},{"key":"bibr6-095646249400500607","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.18.1.170-177.1983"},{"key":"bibr7-095646249400500607","unstructured":"Department of Health Government Statistical Service DH Statistics Division 2B. New cases seen at NHS Genito-Urinary Medicine Clinics in England. 1992 Annual figures. Summary information from Form KC60."},{"key":"bibr8-095646249400500607","first-page":"19","volume":"69","author":"Nahmias AJ","year":"1990","journal-title":"Scand J Infect Dis"},{"key":"bibr9-095646249400500607","unstructured":"Katzenstein DA, Latif A, Bassett MT, Emmanuel JC. Risks for heterosexual transmission of HIV in Zimbabwe.\n                      3rd International Conference on AIDS\n                      , Washington, June 1987. (abstract M.8.3.)."},{"key":"bibr10-095646249400500607","unstructured":"O'Farrell N, Windsor I, Becker P. Risk factors for HIV-1 amongst STD clinic attenders in Durban South Africa.\n                      Sixth International Conference on AIDS\n                      , San Francisco, June 1990 (abstract F.C. 604)."},{"key":"bibr11-095646249400500607","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/165.2.251"},{"key":"bibr12-095646249400500607","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-198902000-00005"},{"key":"bibr13-095646249400500607","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199211000-00012"},{"key":"bibr14-095646249400500607","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199109000-00008"},{"key":"bibr15-095646249400500607","first-page":"370","volume":"69","author":"Horner PJ","year":"1993","journal-title":"Genitourin Med"},{"key":"bibr16-095646249400500607","first-page":"17","volume":"80","author":"O'Farrell N","year":"1991","journal-title":"S Afr Med J"}],"container-title":["International Journal of STD &amp; AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/095646249400500607","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/095646249400500607","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:51:48Z","timestamp":1777675908000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/095646249400500607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,11]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1994,11]]}},"alternative-id":["10.1177\/095646249400500607"],"URL":"https:\/\/doi.org\/10.1177\/095646249400500607","relation":{},"ISSN":["0956-4624","1758-1052"],"issn-type":[{"value":"0956-4624","type":"print"},{"value":"1758-1052","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,11]]}}}